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  4. Inhibitors and Substrates
  5. PTBP1-RNA-binding inhibitor P6 TFA

PTBP1-RNA-binding inhibitor P6 TFA  (Synonyms: PTBP1 α3-helix derived peptide P6 TFA)

Cat. No.: HY-P5960 Purity: 98.43%
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PTBP1-RNA-binding inhibitor P6 (PTBP1 α3-helix derived peptide P6) TFA is a stapled peptide inhibitor of the splicing factor PTBP1, which inhibits alternative splicing events regulated by PTBP1. PTBP1 binds RNA through its RNA recognition motif.

For research use only. We do not sell to patients.

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PTBP1-RNA-binding inhibitor P6 TFA Chemical Structure

PTBP1-RNA-binding inhibitor P6 TFA Chemical Structure

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1 mg USD 190 In-stock
5 mg USD 480 In-stock
10 mg USD 770 In-stock
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Based on 1 publication(s) in Google Scholar

PTBP1-RNA-binding inhibitor P6 TFA Related Antibodies

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Description

PTBP1-RNA-binding inhibitor P6 (PTBP1 α3-helix derived peptide P6) TFA is a stapled peptide inhibitor of the splicing factor PTBP1, which inhibits alternative splicing events regulated by PTBP1. PTBP1 binds RNA through its RNA recognition motif[1].

IC50 & Target

PTBP1[1]
Molecular Weight

1597.86 (free base)

Formula

C73H122N22O19.xC2HF3O2
Appearance

Solid

Color

White to off-white

Sequence

Ac-Asn-Gln-{S5}-Arg-Ala-Gln-{B5}-Ala-Leu-Gln-{R5}-Val-Asn-NH2
Sequence Shortening

Ac-NQ-{S5}-RAQ-{B5}-ALQ-{R5}-VN-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 50 mg/mL

*"≥" means soluble, but saturation unknown.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

Dosing volume
(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References
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PTBP1-RNA-binding inhibitor P6 TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PTBP1-RNA-binding inhibitor P6PTBP1 α3-helix derived peptide P6Othersstapled peptide inhibitorsplicing factorInhibitorinhibitorinhibit

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