1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. PTX-M

PTX-M is an oxidized metabolite of Pentoxifylline (HY-B0715). Pentoxifylline is a phosphodiesterase inhibitor that can be used for the study of peripheral vascular, inflammatory, and immune diseases.

For research use only. We do not sell to patients.

PTX-M Chemical Structure

PTX-M Chemical Structure

CAS No. : 2130882-23-2

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Based on 1 publication(s) in Google Scholar

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Description

PTX-M is an oxidized metabolite of Pentoxifylline (HY-B0715). Pentoxifylline is a phosphodiesterase inhibitor that can be used for the study of peripheral vascular, inflammatory, and immune diseases[1].

Molecular Weight

294.31

Formula

C13H18N4O4

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(C)OCCCCN1C(C2=C(N(C)C1=O)N=CN2C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (339.78 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3978 mL 16.9889 mL 33.9778 mL
5 mM 0.6796 mL 3.3978 mL 6.7956 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3978 mL 16.9889 mL 33.9778 mL 84.9444 mL
5 mM 0.6796 mL 3.3978 mL 6.7956 mL 16.9889 mL
10 mM 0.3398 mL 1.6989 mL 3.3978 mL 8.4944 mL
15 mM 0.2265 mL 1.1326 mL 2.2652 mL 5.6630 mL
20 mM 0.1699 mL 0.8494 mL 1.6989 mL 4.2472 mL
25 mM 0.1359 mL 0.6796 mL 1.3591 mL 3.3978 mL
30 mM 0.1133 mL 0.5663 mL 1.1326 mL 2.8315 mL
40 mM 0.0849 mL 0.4247 mL 0.8494 mL 2.1236 mL
50 mM 0.0680 mL 0.3398 mL 0.6796 mL 1.6989 mL
60 mM 0.0566 mL 0.2831 mL 0.5663 mL 1.4157 mL
80 mM 0.0425 mL 0.2124 mL 0.4247 mL 1.0618 mL
100 mM 0.0340 mL 0.1699 mL 0.3398 mL 0.8494 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
PTX-M
Cat. No.:
HY-171128
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