2. Peptides
  3. Peptide and Derivatives
  4. Peptides for Drug Delivery
  5. Cell-penetrating Peptides
  6. pVEC (Cadherin-5)

pVEC (Cadherin-5) is a cell-penetrating 18-amino acid-long peptide derived from the murine sequence of the cell adhesion molecule vascular endothelial cadherin. pVEC (Cadherin-5) is efficiently and rapidly taken up into cells, it can be used as a carrier peptide.

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pVEC (Cadherin-5) Chemical Structure

pVEC (Cadherin-5) Chemical Structure

CAS No. : 383430-30-6

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Based on 1 publication(s) in Google Scholar

pVEC (Cadherin-5) Related Antibodies

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Description

pVEC (Cadherin-5) is a cell-penetrating 18-amino acid-long peptide derived from the murine sequence of the cell adhesion molecule vascular endothelial cadherin. pVEC (Cadherin-5) is efficiently and rapidly taken up into cells, it can be used as a carrier peptide[1].

In Vitro

pVEC (Cadherin-5) accumulates in nuclear structures and it is highly uptaken by murine brain endothelial cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

pVEC (Cadherin-5) Related Antibodies
Molecular Weight

2209.69

Formula

C98H177N37O21
CAS No.
Appearance

Solid

Color

Off-white to light yellow

Sequence

Leu-Leu-Ile-Ile-Leu-Arg-Arg-Arg-Ile-Arg-Lys-Gln-Ala-His-Ala-his-Ser-Lys-OH
Sequence Shortening

LLIILRRRIRKQAHAHSK
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (45.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4526 mL 2.2628 mL 4.5255 mL
5 mM 0.0905 mL 0.4526 mL 0.9051 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.4526 mL 2.2628 mL 4.5255 mL 11.3138 mL
5 mM 0.0905 mL 0.4526 mL 0.9051 mL 2.2628 mL
10 mM 0.0453 mL 0.2263 mL 0.4526 mL 1.1314 mL
15 mM 0.0302 mL 0.1509 mL 0.3017 mL 0.7543 mL
20 mM 0.0226 mL 0.1131 mL 0.2263 mL 0.5657 mL
25 mM 0.0181 mL 0.0905 mL 0.1810 mL 0.4526 mL
30 mM 0.0151 mL 0.0754 mL 0.1509 mL 0.3771 mL
40 mM 0.0113 mL 0.0566 mL 0.1131 mL 0.2828 mL
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pVEC (Cadherin-5) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

pVEC (Cadherin-5)383430-30-6Otherscell adhesion moleculecell-penetratingcadherincarrier peptideInhibitorinhibitorinhibit

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