2. Metabolic Enzyme/Protease NF-κB
  3. Endogenous Metabolite Keap1-Nrf2
  4. Pyridoxine-d3 hydrochloride

Pyridoxine-d3 hydrochloride  (Synonyms: Pyridoxol-d3 hydrochloride; Vitamin B6-d3 hydrochloride)

Cat. No.: HY-N0682S Purity: ≥99.0%
COA Handling Instructions

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Pyridoxine-d3 (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride. Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.

For research use only. We do not sell to patients.

Pyridoxine-d<sub>3</sub> hydrochloride Chemical Structure

Pyridoxine-d3 hydrochloride Chemical Structure

CAS No. : 1189921-12-7

Size Price Stock Quantity
500 μg USD 420 In-stock
1 mg USD 690 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Pyridoxine-d3 hydrochloride:

Pyridoxine-d3 hydrochloride Related Antibodies

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  • Purity & Documentation

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Description

Pyridoxine-d3 (hydrochloride) is the deuterium labeled Pyridoxine hydrochloride. Pyridoxine hydrochloride (Pyridoxol; Vitamin B6) is a pyridine derivative. Pyridoxine (Pyridoxol; Vitamin B6) exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Pyridoxine-d3 hydrochloride Related Antibodies
Molecular Weight

208.66

Formula

C8H9D3ClNO3
CAS No.
Unlabeled CAS

58-56-0
Appearance

Solid

Color

White to off-white

SMILES

[H]Cl.OCC1=C(C(O)=C(N=C1)C([2H])([2H])[2H])CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (239.62 mM)

DMSO : ≥ 50 mg/mL (239.62 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : ≥ 50 mg/mL (239.62 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.7925 mL 23.9624 mL 47.9249 mL
5 mM 0.9585 mL 4.7925 mL 9.5850 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO / H2O 1 mM 4.7925 mL 23.9624 mL 47.9249 mL 119.8121 mL
5 mM 0.9585 mL 4.7925 mL 9.5850 mL 23.9624 mL
10 mM 0.4792 mL 2.3962 mL 4.7925 mL 11.9812 mL
15 mM 0.3195 mL 1.5975 mL 3.1950 mL 7.9875 mL
20 mM 0.2396 mL 1.1981 mL 2.3962 mL 5.9906 mL
25 mM 0.1917 mL 0.9585 mL 1.9170 mL 4.7925 mL
30 mM 0.1597 mL 0.7987 mL 1.5975 mL 3.9937 mL
40 mM 0.1198 mL 0.5991 mL 1.1981 mL 2.9953 mL
50 mM 0.0958 mL 0.4792 mL 0.9585 mL 2.3962 mL
60 mM 0.0799 mL 0.3994 mL 0.7987 mL 1.9969 mL
80 mM 0.0599 mL 0.2995 mL 0.5991 mL 1.4977 mL
100 mM 0.0479 mL 0.2396 mL 0.4792 mL 1.1981 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Pyridoxine-d3 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pyridoxine-d31189921-12-7Pyridoxol-d3Vitamin B6-d3Endogenous MetaboliteKeap1-Nrf2Inhibitorinhibitorinhibit

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