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  3. Isotope-Labeled Compounds
  4. Pyridoxine-d5

Pyridoxine-d5  (Synonyms: Pyridoxol-d5)

Cat. No.: HY-B1328S Purity: ≥95.0%
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Pyridoxine-d5 (Pyridoxol-d5) is a deuterium labeled Pyridoxine (HY-B1328). Pyridoxine (Pyridoxol) is a pyridine derivative. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.

For research use only. We do not sell to patients.

Pyridoxine-d<sub>5</sub> Chemical Structure

Pyridoxine-d5 Chemical Structure

CAS No. : 688302-31-0

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1 mg USD 848 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Pyridoxine-d5:

Pyridoxine-d5 Related Antibodies

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Description

Pyridoxine-d5 (Pyridoxol-d5) is a deuterium labeled Pyridoxine (HY-B1328). Pyridoxine (Pyridoxol) is a pyridine derivative. Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf-2/HO-1 pathway.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Pyridoxine-d5 Related Antibodies
Molecular Weight

174.21

Formula

C8H6D5NO3
CAS No.
Unlabeled CAS

65-23-6
Appearance

Solid

Color

White to off-white

SMILES

OCC1=C(O)C(C([2H])([2H])[2H])=NC=C1C([2H])([2H])O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (574.02 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.7402 mL 28.7010 mL 57.4020 mL
5 mM 1.1480 mL 5.7402 mL 11.4804 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.7402 mL 28.7010 mL 57.4020 mL 143.5050 mL
5 mM 1.1480 mL 5.7402 mL 11.4804 mL 28.7010 mL
10 mM 0.5740 mL 2.8701 mL 5.7402 mL 14.3505 mL
15 mM 0.3827 mL 1.9134 mL 3.8268 mL 9.5670 mL
20 mM 0.2870 mL 1.4350 mL 2.8701 mL 7.1752 mL
25 mM 0.2296 mL 1.1480 mL 2.2961 mL 5.7402 mL
30 mM 0.1913 mL 0.9567 mL 1.9134 mL 4.7835 mL
40 mM 0.1435 mL 0.7175 mL 1.4350 mL 3.5876 mL
50 mM 0.1148 mL 0.5740 mL 1.1480 mL 2.8701 mL
60 mM 0.0957 mL 0.4783 mL 0.9567 mL 2.3917 mL
80 mM 0.0718 mL 0.3588 mL 0.7175 mL 1.7938 mL
100 mM 0.0574 mL 0.2870 mL 0.5740 mL 1.4350 mL
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Pyridoxine-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pyridoxine-d5688302-31-0Pyridoxol-d5Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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