Pyrrothiogatain

Cat. No.: HY-138113 Purity: 96.77%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Pyrrothiogatain is an inhibitor for transcription factor GATA. Pyrrothiogatain inhibits the DNA-binding activity of GATA3, inhibits the T helper 2 (Th2) cell differentiation and expression of Th2 cytokines. Pyrrothiogatain is potential in Th2 related allergic disorders.

For research use only. We do not sell to patients.

Pyrrothiogatain Chemical Structure

CAS No. : 477888-48-5

Size	Price	Stock	Quantity
5 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 150	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 240	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 360	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

221.28

Formula

C₁₁H₁₁NO₂S

CAS No.

477888-48-5

Appearance

Solid

Color

Brown to orange

SMILES

O=C(C1=C(N2C(C)=CC=C2C)C=CS1)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (564.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.5192 mL	22.5958 mL	45.1916 mL
5 mM	0.9038 mL	4.5192 mL	9.0383 mL
10 mM	0.4519 mL	2.2596 mL	4.5192 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 96.77%

Select Batch:

Data Sheet (276 KB) SDS (393 KB)

COA (259 KB) HNMR (243 KB) LCMS (96 KB)

Handling Instructions (2659 KB)

References

[1]. Nomura S, et al., Pyrrothiogatain acts as an inhibitor of GATA family proteins and inhibits Th2 cell differentiation in vitro. Sci Rep. 2019 Nov 22;9(1):17335. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.5192 mL	22.5958 mL	45.1916 mL	112.9790 mL
	5 mM	0.9038 mL	4.5192 mL	9.0383 mL	22.5958 mL
	10 mM	0.4519 mL	2.2596 mL	4.5192 mL	11.2979 mL
	15 mM	0.3013 mL	1.5064 mL	3.0128 mL	7.5319 mL
	20 mM	0.2260 mL	1.1298 mL	2.2596 mL	5.6490 mL
	25 mM	0.1808 mL	0.9038 mL	1.8077 mL	4.5192 mL
	30 mM	0.1506 mL	0.7532 mL	1.5064 mL	3.7660 mL
	40 mM	0.1130 mL	0.5649 mL	1.1298 mL	2.8245 mL
	50 mM	0.0904 mL	0.4519 mL	0.9038 mL	2.2596 mL
	60 mM	0.0753 mL	0.3766 mL	0.7532 mL	1.8830 mL
	80 mM	0.0565 mL	0.2824 mL	0.5649 mL	1.4122 mL
	100 mM	0.0452 mL	0.2260 mL	0.4519 mL	1.1298 mL