Pyruvic acid-¹³C (Synonyms: Acetylformic acid-¹³C)

Cat. No.: HY-Y0781S1 Purity: 98.71%: FAQs
Data Sheet SDS COA Handling Instructions

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Pyruvic acid-¹³C is the ¹³C labeled Pyruvic acid[1]. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats[2].

For research use only. We do not sell to patients.

Pyruvic acid-<sup>13</sup>C Chemical Structure

Pyruvic acid-¹³C Chemical Structure

CAS No. : 99124-30-8

Size	Price	Stock	Quantity
1 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 95	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 155	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Other Forms of Pyruvic acid-¹³C:

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Description

Pyruvic acid-¹³C is the ¹³C labeled Pyruvic acid[1]. Pyruvic acid is an intermediate metabolite in the metabolism of carbohydrates, proteins, and fats[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

89.05

Formula

C₂¹³CH₄O₃

CAS No.

99124-30-8

Appearance

Liquid (Density: 1.281 g/cm³)

Color

Colorless to light yellow

SMILES

O[13C](C(C)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (1122.96 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	11.2296 mL	56.1482 mL	112.2965 mL
5 mM	2.2459 mL	11.2296 mL	22.4593 mL
10 mM	1.1230 mL	5.6148 mL	11.2296 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.71%

Select Batch:

Data Sheet (273 KB) SDS (416 KB)

COA (251 KB) HNMR (222 KB) RP-HPLC (80 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. Kładna A, et al. Reactivity of pyruvic acid and its derivatives towards reactive oxygen species. Luminescence. 2015 Nov;30(7):1153-8. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	11.2296 mL	56.1482 mL	112.2965 mL	280.7411 mL
	5 mM	2.2459 mL	11.2296 mL	22.4593 mL	56.1482 mL
	10 mM	1.1230 mL	5.6148 mL	11.2296 mL	28.0741 mL
	15 mM	0.7486 mL	3.7432 mL	7.4864 mL	18.7161 mL
	20 mM	0.5615 mL	2.8074 mL	5.6148 mL	14.0371 mL
	25 mM	0.4492 mL	2.2459 mL	4.4919 mL	11.2296 mL
	30 mM	0.3743 mL	1.8716 mL	3.7432 mL	9.3580 mL
	40 mM	0.2807 mL	1.4037 mL	2.8074 mL	7.0185 mL
	50 mM	0.2246 mL	1.1230 mL	2.2459 mL	5.6148 mL
	60 mM	0.1872 mL	0.9358 mL	1.8716 mL	4.6790 mL
	80 mM	0.1404 mL	0.7019 mL	1.4037 mL	3.5093 mL
	100 mM	0.1123 mL	0.5615 mL	1.1230 mL	2.8074 mL

Pyruvic acid-¹³C Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pyruvic acid-¹³C99124-30-8Acetylformic acid-¹³CEndogenous MetaboliteInhibitorinhibitorinhibit

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Pyruvic acid-13C (Synonyms: Acetylformic acid-13C)

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