2. Metabolic Enzyme/Protease
  3. Dihydrofolate reductase (DHFR)
  4. QDPR-IN-1

QDPR-IN-1 (Compound 9b) is a potent QDPR inhibitor with an IC50 of 0.72 μM.

For research use only. We do not sell to patients.

QDPR-IN-1 Chemical Structure

QDPR-IN-1 Chemical Structure

CAS No. : 29415-71-2

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10 mg USD 48 In-stock
25 mg USD 95 In-stock
50 mg USD 155 In-stock
100 mg USD 245 In-stock
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Based on 1 publication(s) in Google Scholar

QDPR-IN-1 Related Antibodies

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Description

QDPR-IN-1 (Compound 9b) is a potent QDPR inhibitor with an IC50 of 0.72 μM[1].

Molecular Weight

233.27

Formula

C12H15N3O2
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C1NNC(C2=CC(N(CC)CC)=CC=C12)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 3.12 mg/mL (13.38 mM; ultrasonic and adjust pH to 4 with 1 M HCL; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.2869 mL 21.4344 mL 42.8688 mL
5 mM 0.8574 mL 4.2869 mL 8.5738 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.2869 mL 21.4344 mL 42.8688 mL 107.1719 mL
5 mM 0.8574 mL 4.2869 mL 8.5738 mL 21.4344 mL
10 mM 0.4287 mL 2.1434 mL 4.2869 mL 10.7172 mL
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QDPR-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

QDPR-IN-129415-71-2Dihydrofolate reductase (DHFR)Quinonoid dihydropteridine reductaseQDPRHepG2JurkatSH-SY5YPC12DanticancerInhibitorinhibitorinhibit

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