QST4

Cat. No.: HY-156421 Purity: 99.23%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

QST4 has antitubercular activity, with the MIC value of 6.25 μM in Mycobacterium tuberculosis H37Rv.

For research use only. We do not sell to patients.

QST4 Chemical Structure

CAS No. : 2991427-35-9

Size	Price	Stock	Quantity
1 mg	USD 69	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 164	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 244	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Biological Activity
Purity & Documentation
References
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Description

QST4 has antitubercular activity, with the MIC value of 6.25 μM in Mycobacterium tuberculosis H37Rv^[1].

Molecular Weight

392.88

Formula

C₁₆H₁₃ClN₄O₂S₂

CAS No.

2991427-35-9

Appearance

Solid

Color

White to off-white

SMILES

O=S(NNC(NC1=CC(Cl)=CC=C1)=S)(C2=CC=CC3=CC=CN=C32)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (318.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5453 mL	12.7265 mL	25.4531 mL
5 mM	0.5091 mL	2.5453 mL	5.0906 mL
10 mM	0.2545 mL	1.2727 mL	2.5453 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.23%

Select Batch:

Data Sheet (269 KB) SDS (252 KB)

COA (249 KB) HNMR (257 KB) LCMS (93 KB)

Handling Instructions (2659 KB)

References

[1]. Novel Quinoline-Based Thiosemicarbazide Derivatives: Synthesis, DFT Calculations, and Investigation of Antitubercular, Antibacterial, and Antifungal Activities

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.5453 mL	12.7265 mL	25.4531 mL	63.6327 mL
	5 mM	0.5091 mL	2.5453 mL	5.0906 mL	12.7265 mL
	10 mM	0.2545 mL	1.2727 mL	2.5453 mL	6.3633 mL
	15 mM	0.1697 mL	0.8484 mL	1.6969 mL	4.2422 mL
	20 mM	0.1273 mL	0.6363 mL	1.2727 mL	3.1816 mL
	25 mM	0.1018 mL	0.5091 mL	1.0181 mL	2.5453 mL
	30 mM	0.0848 mL	0.4242 mL	0.8484 mL	2.1211 mL
	40 mM	0.0636 mL	0.3182 mL	0.6363 mL	1.5908 mL
	50 mM	0.0509 mL	0.2545 mL	0.5091 mL	1.2727 mL
	60 mM	0.0424 mL	0.2121 mL	0.4242 mL	1.0605 mL
	80 mM	0.0318 mL	0.1591 mL	0.3182 mL	0.7954 mL
	100 mM	0.0255 mL	0.1273 mL	0.2545 mL	0.6363 mL

QST4 Related Classifications

Infection

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

QST42991427-35-9QST 4QST-4BacterialAntimicrobial AgentMycobacterium tuberculosis H37RvInhibitorinhibitorinhibit

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