2. PI3K/Akt/mTOR Autophagy Apoptosis Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. PI3K Autophagy Mitophagy Apoptosis Reactive Oxygen Species
  4. Quercetin

Quercetin GMP is Quercetin (HY-18085) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Quercetin is a flavonoid antioxidant, a PI3K inhibitor and a SIRT1 Activator.

For research use only. We do not sell to patients.

Quercetin Chemical Structure

Quercetin Chemical Structure

CAS No. : 117-39-5

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Other Forms of Quercetin:

Quercetin Related Antibodies

Top Publications Citing Use of Products

62 Publications Citing Use of MCE Quercetin

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    Quercetin purchased from MedChemExpress. Usage Cited in: Life Sci. 2020 Sep 15;257:118116.  [Abstract]

    NRK-52E cells are treated with Quercetin (Quer, 20 μM) for 2 h prior to incubation with AngII (100 nM) for another 72 h. The expression of p21 and p16ink4a are detected using Western blotting, and quantitative analyses are performed.

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    Description

    Quercetin GMP is Quercetin (HY-18085) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Quercetin is a flavonoid antioxidant, a PI3K inhibitor and a SIRT1 Activator[1][2][3][4][5][6].

    In Vitro

    Quercetin GMP (10, 50 and 100 μM) increases osteogenesis of mesenchymal stem cells (mASCs)[1].
    Quercetin GMP (0.1-10 μM) dose-dependently decreases osteoclastogenesis induced by RANKL[2].
    Quercetin GMP (2 μM) dose-dependently enhances the osteogenic differentiation and angiogenic factor secretion of rat bone marrow-derived mesenchymal stem cells (rBMSCs)[3].
    Quercetin GMP (2-5 μM) inhibits bone resorption via inhibiting the differentiation and activation of osteoclasts[4].
    Quercetin (5 μM; 2-4 d) dose-dependently increases osteogenic differentiation[5].
    Quercetin (0-5 μM; 6 d) incresese osteoblastic differentiation and extracellular matrix production and mineralization[6].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Quercetin Related Antibodies
    Clinical Trial
    Molecular Weight

    302.24

    Formula

    C15H10O7
    CAS No.
    SMILES

    OC1=C(C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C3C1=O
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
    References
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    Quercetin Related Classifications

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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Quercetin (GMP)117-39-5PI3KAutophagyMitophagyApoptosisReactive Oxygen SpeciesPhosphoinositide 3-kinaseMitochondrial AutophagyGMPcell therapyosteogenesisBMSCmASCbone resorptiodifferentiationInhibitorinhibitorinhibit

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