Quercetin

Name: Quercetin
Brand: MedChemExpress
SKU: HY-18085
Rating: 5.0 (84 reviews)

Cat. No.: HY-18085 Purity: 98.45%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC₅₀ of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively.

For research use only. We do not sell to patients.

Quercetin Chemical Structure

CAS No. : 117-39-5

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 55	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 55	In-stock	Estimated Time of Arrival: December 31
Solid
500 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
1 g	USD 60	In-stock	Estimated Time of Arrival: December 31
5 g	USD 96	In-stock	Estimated Time of Arrival: December 31
10 g		Get quote
50 g		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 84 publication(s) in Google Scholar

Other Forms of Quercetin:

Quercetin-d₃ hydrate Get quote
Quercetin-d₅ Get quote
Quercetin-d₃ Get quote
Quercetin-¹³C₃ Get quote
Quercetin hydrate Get quote
Quercetin dihydrate Get quote
Quercetin (GMP) Get quote
Quercetin (Standard) Get quote

83 Publications Citing Use of MCE Quercetin

: Quercetin purchased from MedChemExpress. Usage Cited in: Life Sci. 2020 Sep 15;257:118116. [Abstract]; NRK-52E cells are treated with Quercetin (Quer, 20 μM) for 2 h prior to incubation with AngII (100 nM) for another 72 h. The expression of p21 and p16ink4a are detected using Western blotting, and quantitative analyses are performed.

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All PI3K Isoform Specific Products:

View All Isoforms

PI3Kα PI3Kβ PI3Kγ PI3Kδ PI3KC2α PI3KC2β PI3KC2γ Vps34 PI3K PI3KC3 p120γ

Biological Activity
Protocol
Purity & Documentation
References
Customer Review

Description

Quercetin, a natural flavonoid, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC₅₀ of 2.4 μM, 3.0 μM and 5.4 μM for PI3K γ, PI3K δ and PI3K β, respectively^[1].

IC₅₀ & Target^[1]

PI3Kδ

2.4 μM (IC₅₀)

PI3Kγ

3 μM (IC₅₀)

PI3Kβ

5.4 μM (IC₅₀)

Autophagy

Mitophagy

Cellular Effect

Cell Line	Type	Value	Description	References
2008	IC₅₀	21.18 μM Compound: 1, Que	Cytotoxicity against human 2008 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human 2008 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 25906385]
A2780	GI₅₀	19.7 μM Compound: Quercetin	Growth inhibition of human A2780 cells incubated for 72 hrs by trypan blue assay Growth inhibition of human A2780 cells incubated for 72 hrs by trypan blue assay	[PMID: 32435372]
A-375	IC₅₀	25.13 μM Compound: 1, Que	Cytotoxicity against human A375 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human A375 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 25906385]
A-431	IC₅₀	1.8 μg/mL Compound: quercetin	Inhibition of phosphatidylinositol 4-kinase in human A431 cell membrane by liquid scintillation counting Inhibition of phosphatidylinositol 4-kinase in human A431 cell membrane by liquid scintillation counting	[PMID: 1666120]
A-431	IC₅₀	23.04 μM Compound: 1, Que	Cytotoxicity against human A431 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human A431 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 25906385]
A-431	IC₅₀	34.37 μM Compound: 1, Que	Cytotoxicity against cisplatin-resistant human A431 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against cisplatin-resistant human A431 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 25906385]
A549	IC₅₀	> 10 μg/mL Compound: Compound 4	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 25862199]
A549	IC₅₀	> 10 μM Compound: 10	Cytotoxicity against human A549 cells after 48 hrs by SRB assay Cytotoxicity against human A549 cells after 48 hrs by SRB assay	[PMID: 28165740]
A549	IC₅₀	> 20 mg/mL Compound: 18	Cytotoxicity against human A549 cells after 3 days by SRB assay Cytotoxicity against human A549 cells after 3 days by SRB assay	[PMID: 15568778]
A549	IC₅₀	13 μM Compound: Quer	Cytotoxicity against human A549 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 28654265]
A549	IC₅₀	6.2 μM Compound: 1	Anticancer activity against human A549 cells by HTS assay Anticancer activity against human A549 cells by HTS assay	[PMID: 25139569]
B16-4A5	IC₅₀	15 μM Compound: 7	Inhibition of melanogenesis in theophylline-stimulated mouse B16-4A5 cells after 72 hrs by microplate reader analysis Inhibition of melanogenesis in theophylline-stimulated mouse B16-4A5 cells after 72 hrs by microplate reader analysis	[PMID: 25987378]
B16-4A5	IC₅₀	15 μM Compound: 17	Inhibition of theophylline-stimulated melanogenesis in mouse B16-4A5 cells after 72 hrs Inhibition of theophylline-stimulated melanogenesis in mouse B16-4A5 cells after 72 hrs	[PMID: 20189399]
BALB/3T3	IC₅₀	217 μM Compound: 5	Growth inhibition of BALB/c mouse cloned 3T3/A31 cells after 72 hrs by nigrosin assay Growth inhibition of BALB/c mouse cloned 3T3/A31 cells after 72 hrs by nigrosin assay	[PMID: 10096863]
BT-549	IC₅₀	> 10 μM Compound: 10	Cytotoxicity against human BT549 cells after 48 hrs by SRB assay Cytotoxicity against human BT549 cells after 48 hrs by SRB assay	[PMID: 28165740]
BV-2	IC₅₀	10 μM Compound: Quercetin	Antiinflammatory activity in human BV2 cells assessed as inhibition of LPS-induced nitric oxide production by Griess assay Antiinflammatory activity in human BV2 cells assessed as inhibition of LPS-induced nitric oxide production by Griess assay	[PMID: 24707938]
BV-2	EC₅₀	10.5 μM Compound: Quercetin	Inhibition of LPS-induced NO production in mouse BV-2 cells incubated for 24 hrs by Griess reagent based assay Inhibition of LPS-induced NO production in mouse BV-2 cells incubated for 24 hrs by Griess reagent based assay	[PMID: 34315042]
BV-2	EC₅₀	11 μM Compound: quercetin	Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-stimulated NO production after 24 hrs by Griess assay Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-stimulated NO production after 24 hrs by Griess assay	[PMID: 26473791]
BV-2	IC₅₀	15.13 μM Compound: Quercetin	Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs measured after 15 mins by Griess assay Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs measured after 15 mins by Griess assay	[PMID: 27335254]
BV-2	IC₅₀	16.3 μM Compound: Quercetin	Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-stimulated nitric oxide production by Griess reagent based spectrophotometric analysis Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-stimulated nitric oxide production by Griess reagent based spectrophotometric analysis	[PMID: 29122483]
BV-2	IC₅₀	17.4 μM Compound: quercetin	Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-stimulated nitric oxide production after 24 hrs by Griess assay Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-stimulated nitric oxide production after 24 hrs by Griess assay	[PMID: 26327273]
BV-2	IC₅₀	19.11 μM Compound: 10	Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitrite production after 24 hrs by Griess assay Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitrite production after 24 hrs by Griess assay	[PMID: 28165740]
BV-2	IC₅₀	2.4 μM Compound: Quercetin	Antineuroinflammatory activity in mouse BV-2 cells assessed as inhibition of LPS-induced NO production measured after 24 hrs by Griess reagent based assay Antineuroinflammatory activity in mouse BV-2 cells assessed as inhibition of LPS-induced NO production measured after 24 hrs by Griess reagent based assay	[PMID: 31244147]
BV-2	IC₅₀	2.4 μM Compound: Quercetin	Inhibition of LPS-induced nitric oxide production in mouse BV2 cells after 24 hrs by Griess assay Inhibition of LPS-induced nitric oxide production in mouse BV2 cells after 24 hrs by Griess assay	[PMID: 30132670]
BV-2	IC₅₀	2.45 μM Compound: Quercetin	Antineuroinflammatory activity against mouse BV-2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs by Griess assay Antineuroinflammatory activity against mouse BV-2 cells assessed as inhibition of LPS-induced NO production incubated for 24 hrs by Griess assay	[PMID: 34978437]
BV-2	IC₅₀	39.46 μM Compound: 1	Antineuroinflammatory activity in human BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs in presence of LPS by Griess reaction Antineuroinflammatory activity in human BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs in presence of LPS by Griess reaction	[PMID: 27623545]
BV-2	IC₅₀	4.3 μM Compound: Quercetin	Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay	[PMID: 30119995]
BV-2	IC₅₀	4.3 μM Compound: Quercetin	Inhibition of LPS-stimulated NO production in human BV2 cells after 24 hrs by Griess assay Inhibition of LPS-stimulated NO production in human BV2 cells after 24 hrs by Griess assay	[PMID: 25127164]
BV-2	IC₅₀	6.5 μM Compound: Quercetin	Inhibition of NO production in LPS-induced mouse BV-2 cells incubated for 24 hrs by Griess reagent based microplate reader analysis Inhibition of NO production in LPS-induced mouse BV-2 cells incubated for 24 hrs by Griess reagent based microplate reader analysis	[PMID: 36579935]
BV-2	IC₅₀	7.2 μM Compound: Quercetin	Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by griess assay Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by griess assay	[PMID: 29303577]
BV-2	IC₅₀	8.7 μM Compound: Quercetin	Inhibition of LPS-induced nitric oxide production in human BV2 cells after 24 hrs by Griess assay Inhibition of LPS-induced nitric oxide production in human BV2 cells after 24 hrs by Griess assay	[PMID: 26696523]
BV-2	EC₅₀	9.56 μM Compound: Qc	Inhibition of LPS induced NO production in mouse BV-2 cells by Griess reagent based analysis Inhibition of LPS induced NO production in mouse BV-2 cells by Griess reagent based analysis	[PMID: 34875520]
BXPC-3	IC₅₀	16 μM Compound: Quer	Cytotoxicity against human BxPC3 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human BxPC3 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 28654265]
BXPC-3	IC₅₀	24.12 μM Compound: 1, Que	Cytotoxicity against human BxPC3 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human BxPC3 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 25906385]
C13	IC₅₀	37.62 μM Compound: 1, Que	Cytotoxicity against human C13 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human C13 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 25906385]
C2C12	IC₅₀	30.79 μg/mL Compound: 3	Cytotoxicity against mouse C2C12 cells assessed as reduction in cell viability by MTT assay Cytotoxicity against mouse C2C12 cells assessed as reduction in cell viability by MTT assay	[PMID: 33412152]
C6	IC₅₀	18.38 μM Compound: 51	Inhibition of cell proliferation of rat C6 cells assessed as cell viability after 72 hrs by sulforhodamine B assay Inhibition of cell proliferation of rat C6 cells assessed as cell viability after 72 hrs by sulforhodamine B assay	[PMID: 25442304]
C8166	CC₅₀	104.9 μg/mL Compound: 1	Cytotoxicity against human C8166 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human C8166 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 24794743]
C8166	EC₅₀	2.05 μg/mL Compound: 1	Antiviral activity against HIV-1 3B infected in human C8166 cells assessed as inhibition of virus-induced cytopathogenicity by measuring syncytial cell number after 3 days by inverted microscopic analysis Antiviral activity against HIV-1 3B infected in human C8166 cells assessed as inhibition of virus-induced cytopathogenicity by measuring syncytial cell number after 3 days by inverted microscopic analysis	[PMID: 24794743]
Calu-1	IC₅₀	23.58 μM Compound: 1	Anticancer activity against human Calu1 cells by HTS assay Anticancer activity against human Calu1 cells by HTS assay	[PMID: 25139569]
CCRF-CEM	IC₅₀	> 10 μg/mL Compound: 8	Cytotoxicity against human CEM cells after 3 days by MTT assay Cytotoxicity against human CEM cells after 3 days by MTT assay	[PMID: 11421746]
COLO 201	IC₅₀	19 μM Compound: Quer	Cytotoxicity against human COLO201 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human COLO201 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 28654265]
CWR22R	IC₅₀	15.5 μM Compound: 16	Antiproliferative activity against human 22Rv1 cells incubated up to 144 hrs by Coulter particle count and size analyzer Antiproliferative activity against human 22Rv1 cells incubated up to 144 hrs by Coulter particle count and size analyzer	[PMID: 22789812]
DU-145	EC₅₀	> 100 μM Compound: Quercetin	Antiproliferative activity against human DU145 cells after 24 hrs by MTT assay Antiproliferative activity against human DU145 cells after 24 hrs by MTT assay	[PMID: 21090565]
DU-145	IC₅₀	> 100 μM Compound: Quercetin	Antiproliferative activity against human DU145 cells after 3 days by WST-1 assay Antiproliferative activity against human DU145 cells after 3 days by WST-1 assay	[PMID: 30165345]
DU-145	IC₅₀	> 100 μM Compound: 1	Antiproliferative activity against human DU145 cells after 3 days by WST-1 assay Antiproliferative activity against human DU145 cells after 3 days by WST-1 assay	[PMID: 28760528]
DU-145	IC₅₀	> 100 μM Compound: Quercetin	Cytotoxicity against human androgen-independent DU145 cells assessed as inhibition of cell viability after 3 days by WST-1 cell proliferation assay Cytotoxicity against human androgen-independent DU145 cells assessed as inhibition of cell viability after 3 days by WST-1 cell proliferation assay	[PMID: 26341135]
H9	EC₅₀	132 μM Compound: 4	Antiviral activity against HIV1 3B infected in human H9 cells assessed as inhibition of viral replication after 3 days by p24 antigen capture assay Antiviral activity against HIV1 3B infected in human H9 cells assessed as inhibition of viral replication after 3 days by p24 antigen capture assay	[PMID: 8158164]
H9	IC₅₀	132 μM Compound: 4	Cytotoxicity against human H9 cells after 3 days Cytotoxicity against human H9 cells after 3 days	[PMID: 8158164]
HCT-116	EC₅₀	> 100 μM Compound: Quercetin	Antiproliferative activity against human HCT116 cells after 24 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 24 hrs by MTT assay	[PMID: 21090565]
HCT-116	IC₅₀	23 μM Compound: 2	Growth inhibition of human HCT116 cells overexpressing PI3Kalpha after 48 hrs by MTT assay Growth inhibition of human HCT116 cells overexpressing PI3Kalpha after 48 hrs by MTT assay	[PMID: 22212721]
HCT-116	IC₅₀	43.87 μM Compound: Quercetin	Cytotoxicity against human HCT-116 cells overexpressing MCT-1 assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human HCT-116 cells overexpressing MCT-1 assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 33221062]
HCT-116	IC₅₀	5.7 μM Compound: 2	Growth inhibition of human HCT116 cells overexpressing PI3Kalpha H1047R mutant after 48 hrs by MTT assay Growth inhibition of human HCT116 cells overexpressing PI3Kalpha H1047R mutant after 48 hrs by MTT assay	[PMID: 22212721]
HCT-116	IC₅₀	6.7 μM Compound: 2	Growth inhibition of human HCT116 cells after 48 hrs by MTT assay Growth inhibition of human HCT116 cells after 48 hrs by MTT assay	[PMID: 22212721]
HCT-15	IC₅₀	16.35 μM Compound: 1, Que	Cytotoxicity against human HCT15 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HCT15 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 25906385]
HEK293	IC₅₀	0.68 μM Compound: 7a	Inhibition of NOX4 expressed in HEK293 FS cells assessed as H2O2 production by H2O2/Tyr/LPO assay Inhibition of NOX4 expressed in HEK293 FS cells assessed as H2O2 production by H2O2/Tyr/LPO assay	[PMID: 20731357]
HEK293	IC₅₀	54.65 μM Compound: 1, Que	Cytotoxicity against HEK293 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against HEK293 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 25906385]
HEK293	IC₅₀	6.5 μM Compound: 22	Inhibition of human TRPC5 expressed in HEK293 cells assessed as reduction in gadolinium-induced calcium entry after 30 mins by fluo-4 dye based fluorescence assay Inhibition of human TRPC5 expressed in HEK293 cells assessed as reduction in gadolinium-induced calcium entry after 30 mins by fluo-4 dye based fluorescence assay	[PMID: 30943030]
HeLa	IC₅₀	≥ 10 μM Compound: quercetin	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 19278239]
HeLa	GI₅₀	17.7 μM Compound: Quercetin	Growth inhibition of human HeLa cells incubated for 72 hrs by trypan blue assay Growth inhibition of human HeLa cells incubated for 72 hrs by trypan blue assay	[PMID: 32435372]
HeLa	IC₅₀	22.5 μM Compound: Quercetin	Cytotoxicity against human HeLa cells overexpressing MCT-1 assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human HeLa cells overexpressing MCT-1 assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 33221062]
HeLa	IC₅₀	3.56 μM Compound: 1	Anticancer activity against human HeLa cells by HTS assay Anticancer activity against human HeLa cells by HTS assay	[PMID: 25139569]
HeLa	IC₅₀	4 μM Compound: 30	Cytotoxicity against human HeLa cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay	[PMID: 33355454]
HeLa	IC₅₀	8.26 μg/mL Compound: Compound 4	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 25862199]
HepG2	IC₅₀	> 10 μM Compound: quercetin	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 19583252]
HepG2	IC₅₀	11 μM Compound: Quercetin	Antioxidant activity in human HepG2 cells assessed as inhibition of ABAP-induced intracellular peroxyl radical scavenging activity by measuring ROS production measured every 5 mins for 1 hr by absorbance assay Antioxidant activity in human HepG2 cells assessed as inhibition of ABAP-induced intracellular peroxyl radical scavenging activity by measuring ROS production measured every 5 mins for 1 hr by absorbance assay	[PMID: 24471493]
HepG2	IC₅₀	12 μM Compound: Quercetin	Antioxidant activity in human HepG2 cells assessed as inhibition of ABAP-induced peroxyl radical generation incubated for 60 mins measured for 60 mins by DCFH-DA probe based fluorescence assay Antioxidant activity in human HepG2 cells assessed as inhibition of ABAP-induced peroxyl radical generation incubated for 60 mins measured for 60 mins by DCFH-DA probe based fluorescence assay	[PMID: 29553260]
HepG2	IC₅₀	30.9 μM Compound: 32	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 21726077]
HepG2	EC₅₀	4.63 μM Compound: QE	Antioxidant activity in human HepG2 cells assessed as decrease in fluorescence level after 2.5 hrs measured every 5 mins for 1 hr by DCFH-DA staining based fluorescence assay Antioxidant activity in human HepG2 cells assessed as decrease in fluorescence level after 2.5 hrs measured every 5 mins for 1 hr by DCFH-DA staining based fluorescence assay	[PMID: 26974372]
HepG2	IC₅₀	65 μM Compound: Quercetin	Antioxidant activity in human HepG2 cells assessed as inhibition of cumene hydroperoxide-mediated lipid peroxidation incubated for 60 mins followed by cumOOH addition for 60 mins measured for 60 mins by C11-BODIPY probe based fluorescence assay Antioxidant activity in human HepG2 cells assessed as inhibition of cumene hydroperoxide-mediated lipid peroxidation incubated for 60 mins followed by cumOOH addition for 60 mins measured for 60 mins by C11-BODIPY probe based fluorescence assay	[PMID: 29553260]
HepG2 2.2.15	CC₅₀	38.1 μM Compound: quercetin	Cytotoxicity against human HepG2(2.2.15) cells after 8 days by MTT assay Cytotoxicity against human HepG2(2.2.15) cells after 8 days by MTT assay	[PMID: 21401115]
HL-60	IC₅₀	> 10 μg/mL Compound: 8	Cytotoxicity against human HL60 cells after 3 days by MTT assay Cytotoxicity against human HL60 cells after 3 days by MTT assay	[PMID: 11421746]
HL-60	IC₅₀	10 ng/mL Compound: Quercetin	Growth inhibition of human HL60 cells after 72 hrs by MTT assay Growth inhibition of human HL60 cells after 72 hrs by MTT assay	[PMID: 31398616]
HL-60	IC₅₀	47 μM Compound: Quercetin	Cytotoxicity against human HL60 cells after 72 hrs by MTT assay Cytotoxicity against human HL60 cells after 72 hrs by MTT assay	[PMID: 25014747]
HL-60	IC₅₀	58 μM Compound: Quercetin	Cytotoxicity against human HL60 cells after 46 hrs by MTT assay Cytotoxicity against human HL60 cells after 46 hrs by MTT assay	[PMID: 23756061]
HOP-62	IC₅₀	7.52 μM Compound: 1	Anticancer activity against human HOP62 cells by HTS assay Anticancer activity against human HOP62 cells by HTS assay	[PMID: 25139569]
HS27	EC₅₀	> 100 μM Compound: Quercetin	Antiproliferative activity against human HS27 cells after 24 hrs by MTT assay Antiproliferative activity against human HS27 cells after 24 hrs by MTT assay	[PMID: 21090565]
HT-22	EC₅₀	11.52 μM Compound: Quercetin	Cytotoxicity against mouse HT22 cells after 24 hrs by MTT assay Cytotoxicity against mouse HT22 cells after 24 hrs by MTT assay	[PMID: 24602904]
HT-22	EC₅₀	3.13 μM Compound: Quercetin	Neuroprotective activity in mouse HT22 cells assessed as protection against glutamate-induced oxidative damage after 24 hrs by MTT assay Neuroprotective activity in mouse HT22 cells assessed as protection against glutamate-induced oxidative damage after 24 hrs by MTT assay	[PMID: 24602904]
HT-29	IC₅₀	15.4 μM Compound: Quercetin	Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 mins Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 mins	[PMID: 24900447]
HT-29	IC₅₀	18 μM Compound: Quer	Cytotoxicity against human HT-29 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human HT-29 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 28654265]
HT-29	EC₅₀	8.02 μM Compound: Quercetin	Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assay Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assay	[PMID: 24900447]
Huh-7	CC₅₀	> 50 μM Compound: 35	Cytotoxicity against human Huh7.5.1 cells by MTT assay Cytotoxicity against human Huh7.5.1 cells by MTT assay	[PMID: 22445328]
Huh-7	EC₅₀	19.8 μM Compound: 35	Antiviral activity against HCV JFH-1 J399EM infected in Human Huh7.5.1 cells assessed as suppression of viral replication after 72 hrs by EGFP assay Antiviral activity against HCV JFH-1 J399EM infected in Human Huh7.5.1 cells assessed as suppression of viral replication after 72 hrs by EGFP assay	[PMID: 22445328]
J774.2	IC₅₀	125.44 μM Compound: 2	Cytotoxicity against BALB/c mouse J774.2 cells after 72 hrs by trypan blue assay Cytotoxicity against BALB/c mouse J774.2 cells after 72 hrs by trypan blue assay	[PMID: 19489596]
J774.A1	IC₅₀	49.1 μM Compound: 1	Inhibition of LPS-induced NO production in mouse J774.A1 cells pre-incubated with compound for 1 hr followed by LPS stimulation for 24 hrs by ELISA assay Inhibition of LPS-induced NO production in mouse J774.A1 cells pre-incubated with compound for 1 hr followed by LPS stimulation for 24 hrs by ELISA assay	[PMID: 34971873]
Jurkat	IC₅₀	2 μM Compound: Quercetin	Inhibition of chymotrypsin-like activity of human 26S proteasome in human Jurkat cells assessed as decrease in AMC hydrolysis using Z-Gly-Gly-Leu-AMC as substrate after 24 hrs by fluorescence based method Inhibition of chymotrypsin-like activity of human 26S proteasome in human Jurkat cells assessed as decrease in AMC hydrolysis using Z-Gly-Gly-Leu-AMC as substrate after 24 hrs by fluorescence based method	[PMID: 30776692]
Jurkat	IC₅₀	3.5 μM Compound: Quercetin	Inhibition of chymotrypsin-like activity of purified human 20S proteasome expressed in human Jurkat cells assessed as decrease in AMC hydrolysis using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 2 hrs by fluorescence based method Inhibition of chymotrypsin-like activity of purified human 20S proteasome expressed in human Jurkat cells assessed as decrease in AMC hydrolysis using Suc-Leu-Leu-Val-Tyr-AMC as substrate incubated for 2 hrs by fluorescence based method	[PMID: 30776692]
K562	IC₅₀	2.5 μM Compound: Quercetin	Cytotoxicity against human K562 cells assessed as inhibition of cell growth after 5 days by MTT assay Cytotoxicity against human K562 cells assessed as inhibition of cell growth after 5 days by MTT assay	[PMID: 29553260]
L6	IC₅₀	> 30 μg/mL Compound: 17	Antitrypanosomal activity against trypomastigote forms of Trypanosoma cruzi Tulahuen C2C4 infected in rat L6 cells after 96 hrs by photometric method Antitrypanosomal activity against trypomastigote forms of Trypanosoma cruzi Tulahuen C2C4 infected in rat L6 cells after 96 hrs by photometric method	10.1039/C5MD00481K
L929	IC₅₀	> 100 μM Compound: Quercetin	Cytotoxicity against mouse L929 cells after 5 days by MTS assay Cytotoxicity against mouse L929 cells after 5 days by MTS assay	[PMID: 22743241]
L929	EC₅₀	20 μM Compound: quercetin	Inhibition of recombinant human TNF-alpha-induced cytotoxicity of mouse L929 cells assessed as survivality preincubated for 15 mins before TNFalpha addition measured after 24 hrs by crystal violet staining Inhibition of recombinant human TNF-alpha-induced cytotoxicity of mouse L929 cells assessed as survivality preincubated for 15 mins before TNFalpha addition measured after 24 hrs by crystal violet staining	[PMID: 9287415]
L929	EC₅₀	26 μM Compound: quercetin	Inhibition of recombinant human TNF-alpha-induced cytotoxicity of mouse L929 cells assessed as survivality preincubated for 15 mins before TNFalpha addition measured after 24 hrs by [methyl-3H]thymidine incorporation assay Inhibition of recombinant human TNF-alpha-induced cytotoxicity of mouse L929 cells assessed as survivality preincubated for 15 mins before TNFalpha addition measured after 24 hrs by [methyl-3H]thymidine incorporation assay	[PMID: 9287415]
LN-229	IC₅₀	12 μM Compound: Quer	Cytotoxicity against human LN229 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human LN229 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 28654265]
LNCaP	EC₅₀	25 μM Compound: 2, quercetin	Decrease in androgen receptor protein expression in LNCaP cells by Western blotting Decrease in androgen receptor protein expression in LNCaP cells by Western blotting	[PMID: 17383188]
LNCaP	IC₅₀	45.46 μM Compound: 1	Antiproliferative activity against human LNCAP cells after 3 days by WST-1 assay Antiproliferative activity against human LNCAP cells after 3 days by WST-1 assay	[PMID: 28760528]
LNCaP	IC₅₀	45.5 μM Compound: Quercetin	Antiproliferative activity against human LNCAP cells after 3 days by WST-1 assay Antiproliferative activity against human LNCAP cells after 3 days by WST-1 assay	[PMID: 30165345]
LNCaP	IC₅₀	45.5 μM Compound: 1	Antiproliferative activity against human LNCAP cells after 3 days by WST1 assay Antiproliferative activity against human LNCAP cells after 3 days by WST1 assay	[PMID: 27476422]
LNCaP	IC₅₀	45.5 μM Compound: Quercetin	Cytotoxicity against human androgen-dependent LNCAP cells assessed as inhibition of cell viability after 3 days by WST-1 cell proliferation assay Cytotoxicity against human androgen-dependent LNCAP cells assessed as inhibition of cell viability after 3 days by WST-1 cell proliferation assay	[PMID: 26341135]
LOX IMVI	IC₅₀	4.65 μM Compound: 1	Anticancer activity against human LOXIMVI cells by HTS assay Anticancer activity against human LOXIMVI cells by HTS assay	[PMID: 25139569]
M14	IC₅₀	12.77 μM Compound: 1	Anticancer activity against human M14 cells by HTS assay Anticancer activity against human M14 cells by HTS assay	[PMID: 25139569]
MCF-10A	IC₅₀	11.97 μM Compound: Quercetin	Cytotoxicity against human MCF10A cells assessed as decrease in cell viability after 3 days by WST-1 assay Cytotoxicity against human MCF10A cells assessed as decrease in cell viability after 3 days by WST-1 assay	[PMID: 30165345]
MCF7	IC₅₀	> 10 μM Compound: quercetin	Cytotoxicity against human MCF7 cells by MTT assay Cytotoxicity against human MCF7 cells by MTT assay	[PMID: 19583252]
MCF7	EC₅₀	> 100 μM Compound: Quercetin	Antiproliferative activity against human MCF7 cells after 24 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 24 hrs by MTT assay	[PMID: 21090565]
MCF7	IC₅₀	19.5 mg/mL Compound: 18	Cytotoxicity against human MCF7 cells after 3 days by SRB assay Cytotoxicity against human MCF7 cells after 3 days by SRB assay	[PMID: 15568778]
MCF7	IC₅₀	20.9 μM Compound: 1, Que	Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 25906385]
MCF7	IC₅₀	5 μM Compound: Quercetin	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 6 days by SRB assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 6 days by SRB assay	[PMID: 33257172]
MCF7	IC₅₀	7.6 μM Compound: 13	Inhibition of BCRP expressed in MCF-7 MX cells using Hoechst 33342 staining Inhibition of BCRP expressed in MCF-7 MX cells using Hoechst 33342 staining	[PMID: 21354800]
MDA-MB-231	IC₅₀	20 μM Compound: Quer	Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 28654265]
MDCK	CC₅₀	253.8 μM Compound: 4	Cytotoxicity against MDCK cells after 48 hrs by MTT assay Cytotoxicity against MDCK cells after 48 hrs by MTT assay	[PMID: 19729316]
MDCK	CC₅₀	253.8 μM Compound: QR	Cytotoxicity against dog MDCK cells assessed as reduction in cell viability by MTT assay Cytotoxicity against dog MDCK cells assessed as reduction in cell viability by MTT assay	[PMID: 31744778]
MDCK	ED₅₀	48.2 μM Compound: 1	Antiviral activity against influenza A virus (A/swine/OH/511445/2007(H1N1)) Oh7 infected in MDCK cells assessed as inhibition of viral replication after 4 days by quantitative RT-PCR Antiviral activity against influenza A virus (A/swine/OH/511445/2007(H1N1)) Oh7 infected in MDCK cells assessed as inhibition of viral replication after 4 days by quantitative RT-PCR	[PMID: 22115591]
MDCK	IC₅₀	6.9 μM Compound: 13	Inhibition of BCRP expressed in MDCK cells using Hoechst 33342 staining Inhibition of BCRP expressed in MDCK cells using Hoechst 33342 staining	[PMID: 21354800]
MDCK	EC₅₀	84.46 nM Compound: QR	Antiviral activity against Influenza A virus (H1N1) infected in dog MDCK cells assessed as reduction in log2HA titer incubated for 3 to 4 days by CPE assay Antiviral activity against Influenza A virus (H1N1) infected in dog MDCK cells assessed as reduction in log2HA titer incubated for 3 to 4 days by CPE assay	[PMID: 31744778]
Monocyte	IC₅₀	120 μM Compound: quercetin	Inhibition of TNFalpha expression in LPS-stimulated human monocytes treated 30 mins before LPS challenge measured after 14 hrs by ELISA Inhibition of TNFalpha expression in LPS-stimulated human monocytes treated 30 mins before LPS challenge measured after 14 hrs by ELISA	[PMID: 10096854]
MSTO-211H	GI₅₀	> 20 μM Compound: Quercetin	Growth inhibition of human MSTO-211H cells incubated for 72 hrs by trypan blue assay Growth inhibition of human MSTO-211H cells incubated for 72 hrs by trypan blue assay	[PMID: 32435372]
MV4-11	GI₅₀	13.1 μM Compound: 6	Cytotoxicity against human MV4-11 cells harboring FLT3 mutation after 72 hrs by tetrazolium based Ez CyTox cell viability assay Cytotoxicity against human MV4-11 cells harboring FLT3 mutation after 72 hrs by tetrazolium based Ez CyTox cell viability assay	[PMID: 23411073]
N9	IC₅₀	10.22 μM Compound: 2	Antineuroinflammatory activity in mouse N9 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay Antineuroinflammatory activity in mouse N9 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay	[PMID: 28073678]
NALM-6	IC₅₀	77.1 μM Compound: Quercetin	Cytotoxicity against human NALM6 cells after 46 hrs by MTT assay Cytotoxicity against human NALM6 cells after 46 hrs by MTT assay	[PMID: 23756061]
NCI/ADR-RES	IC₅₀	22.15 μM Compound: 1, Que	Cytotoxicity against human MCF7/ADR cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MCF7/ADR cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 25906385]
NCI-H1299	IC₅₀	13.6 μM Compound: 1	Anticancer activity against human H1299 cells by HTS assay Anticancer activity against human H1299 cells by HTS assay	[PMID: 25139569]
NCI-H157	IC₅₀	6 μM Compound: 1	Anticancer activity against human NCI-H157 cells by HTS assay Anticancer activity against human NCI-H157 cells by HTS assay	[PMID: 25139569]
NCI-H1792	IC₅₀	3.85 μM Compound: 1	Anticancer activity against human NCI-H1792 cells by HTS assay Anticancer activity against human NCI-H1792 cells by HTS assay	[PMID: 25139569]
NCI-H1944	IC₅₀	10.18 μM Compound: 1	Anticancer activity against human NCI-H1944 cells by HTS assay Anticancer activity against human NCI-H1944 cells by HTS assay	[PMID: 25139569]
NCI-H460	IC₅₀	12 μM Compound: Quer	Cytotoxicity against human NCI-H460 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 28654265]
NCI-H460	IC₅₀	9.62 μM Compound: 1	Anticancer activity against human H460 cells by HTS assay Anticancer activity against human H460 cells by HTS assay	[PMID: 25139569]
NCI-H522	IC₅₀	5.77 μM Compound: 1	Anticancer activity against human NCI-H522 cells by HTS assay Anticancer activity against human NCI-H522 cells by HTS assay	[PMID: 25139569]
Neutrophil	IC₅₀	0.7 μM Compound: 4i	Inhibition of oxidative burst in PMA-stimulated human neutrophils assessed as inhibition of HOCl-induced oxidation of APF after 6 mins by fluorescence assay Inhibition of oxidative burst in PMA-stimulated human neutrophils assessed as inhibition of HOCl-induced oxidation of APF after 6 mins by fluorescence assay	[PMID: 23871908]
Neutrophil	IC₅₀	1.8 μM Compound: 7	Inhibition of PMA-induced oxidative burst in human neutrophils by APF assay Inhibition of PMA-induced oxidative burst in human neutrophils by APF assay	[PMID: 25151578]
Neutrophil	IC₅₀	11.3 μM Compound: 4i	Inhibition of oxidative burst in PMA-stimulated human neutrophils assessed as inhibition of superoxide anion radical-induced lucigenin oxidation incubated for 5 mins prior to PMA challenge by chemiluminescence assay Inhibition of oxidative burst in PMA-stimulated human neutrophils assessed as inhibition of superoxide anion radical-induced lucigenin oxidation incubated for 5 mins prior to PMA challenge by chemiluminescence assay	[PMID: 23871908]
Neutrophil	IC₅₀	2.4 μM Compound: Quercetin	Inhibition of immune complex-stimulated neutrophil oxidative metabolism in New Zealand white rabbit neutrophils assessed as ROS generation after 30 mins by luminol enhanced chemiluminescence assay Inhibition of immune complex-stimulated neutrophil oxidative metabolism in New Zealand white rabbit neutrophils assessed as ROS generation after 30 mins by luminol enhanced chemiluminescence assay	[PMID: 17804122]
Neutrophil	IC₅₀	2.7 μM Compound: 7	Inhibition of PMA-induced oxidative burst in human neutrophils by amplex red assay Inhibition of PMA-induced oxidative burst in human neutrophils by amplex red assay	[PMID: 25151578]
Neutrophil	IC₅₀	2.8 μM Compound: 7	Inhibition of PMA-induced oxidative burst in human neutrophils by chemiluminescence assay Inhibition of PMA-induced oxidative burst in human neutrophils by chemiluminescence assay	[PMID: 25151578]
Neutrophil	IC₅₀	20.4 μM Compound: Quercetin	Antiinflammatory activity against LPS-stimulated human neutrophils assessed as reduction in TNFalpha production incubated for 1 hr followed by LPS stimulation measured after 18 to 24 hrs by ELISA Antiinflammatory activity against LPS-stimulated human neutrophils assessed as reduction in TNFalpha production incubated for 1 hr followed by LPS stimulation measured after 18 to 24 hrs by ELISA	[PMID: 30109803]
Neutrophil	IC₅₀	26 μM Compound: 4i	Inhibition of oxidative burst in PMA-stimulated human neutrophils assessed as inhibition of ROS-induced luminol oxidation incubated for 5 mins prior to PMA challenge by chemiluminescence assay Inhibition of oxidative burst in PMA-stimulated human neutrophils assessed as inhibition of ROS-induced luminol oxidation incubated for 5 mins prior to PMA challenge by chemiluminescence assay	[PMID: 23871908]
Neutrophil	IC₅₀	33 μM Compound: Quercetin	Antiinflammatory activity against LPS-stimulated human neutrophils assessed as reduction in IL-8 production incubated for 1 hr followed by LPS stimulation measured after 18 to 24 hrs by ELISA Antiinflammatory activity against LPS-stimulated human neutrophils assessed as reduction in IL-8 production incubated for 1 hr followed by LPS stimulation measured after 18 to 24 hrs by ELISA	[PMID: 30109803]
Neutrophil	IC₅₀	4.4 μM Compound: Quercetin	Antiinflammatory activity against f-MLP-stimulated human neutrophils assessed as reduction in ROS production incubated for 40 mins measured at intervals of 2 mins by luminol-dependent chemiluminescence assay Antiinflammatory activity against f-MLP-stimulated human neutrophils assessed as reduction in ROS production incubated for 40 mins measured at intervals of 2 mins by luminol-dependent chemiluminescence assay	[PMID: 30109803]
Neutrophil	IC₅₀	4.7 μM Compound: Quercetin	Inhibition of immune complex-stimulated neutrophil oxidative metabolism in New Zealand white rabbit neutrophils assessed as ROS generation after 30 mins by lucigenin enhanced chemiluminescence assay Inhibition of immune complex-stimulated neutrophil oxidative metabolism in New Zealand white rabbit neutrophils assessed as ROS generation after 30 mins by lucigenin enhanced chemiluminescence assay	[PMID: 17804122]
Neutrophil	IC₅₀	4.86 μM Compound: Quercetin	Antioxidant activity in human neutrophils assessed as inhibition of oxidative burst-induced ROS production by chemiluminescence assay Antioxidant activity in human neutrophils assessed as inhibition of oxidative burst-induced ROS production by chemiluminescence assay	[PMID: 24588269]
Neutrophil	IC₅₀	8 μM Compound: 4i	Inhibition of oxidative burst in PMA-stimulated human neutrophils assessed as inhibition of H2O2-induced oxidation of amplex red incubated for 5 mins prior to PMA challenge by fluorescence assay Inhibition of oxidative burst in PMA-stimulated human neutrophils assessed as inhibition of H2O2-induced oxidation of amplex red incubated for 5 mins prior to PMA challenge by fluorescence assay	[PMID: 23871908]
NHDF	IC₅₀	> 50 μM Compound: 34	Cytotoxicity against NHDF assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against NHDF assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 28671460]
PANC-1	IC₅₀	62 μM Compound: Quer	Cytotoxicity against human PANC1 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human PANC1 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 28654265]
PC-12	EC₅₀	58.4 μM Compound: Quercetin	Neuroprotective activity against H2O2-induced injury in rat PC12 cells treated 2 hrs before H2O2 challenge measured after 4 hrs by MTT assay Neuroprotective activity against H2O2-induced injury in rat PC12 cells treated 2 hrs before H2O2 challenge measured after 4 hrs by MTT assay	[PMID: 19673490]
PC-12	EC₅₀	68.3 μM Compound: Quercetin	Cytoprotective activity against H2O2-induced cell death in rat PC12 cells assessed as increase in cell viability preincubated 2 hrs before H2O2 challenge measured after 4 hrs by MTT assay Cytoprotective activity against H2O2-induced cell death in rat PC12 cells assessed as increase in cell viability preincubated 2 hrs before H2O2 challenge measured after 4 hrs by MTT assay	[PMID: 19362850]
PC-3	IC₅₀	> 100 μM Compound: Quercetin	Antiproliferative activity against human PC3 cells after 3 days by WST-1 assay Antiproliferative activity against human PC3 cells after 3 days by WST-1 assay	[PMID: 30165345]
PC-3	IC₅₀	> 100 μM Compound: 1	Antiproliferative activity against human PC3 cells after 3 days by WST-1 assay Antiproliferative activity against human PC3 cells after 3 days by WST-1 assay	[PMID: 28760528]
PC-3	IC₅₀	> 100 μM Compound: 1	Antiproliferative activity against human PC3 cells after 3 days by WST1 assay Antiproliferative activity against human PC3 cells after 3 days by WST1 assay	[PMID: 27476422]
PC-3	IC₅₀	> 100 μM Compound: Quercetin	Cytotoxicity against human androgen-independent PC3 cells assessed as cell cell viability after 3 days by WST-1 cell proliferation assay Cytotoxicity against human androgen-independent PC3 cells assessed as cell cell viability after 3 days by WST-1 cell proliferation assay	[PMID: 26341135]
Peritoneal macrophage	IC₅₀	36 μM Compound: kp20	Inhibition of LPS-stimulated nitric oxide production in ddy mouse peritoneal macrophages measured after 20 hrs by Greiss method Inhibition of LPS-stimulated nitric oxide production in ddy mouse peritoneal macrophages measured after 20 hrs by Greiss method	[PMID: 27955927]
Peritoneal macrophage cell	IC₅₀	> 100 μM Compound: quercetin	Cytotoxicity against mouse Peritoneal macrophages cells after 72 hrs by MTS assay Cytotoxicity against mouse Peritoneal macrophages cells after 72 hrs by MTS assay	[PMID: 22989363]
Peritoneal macrophage cell	IC₅₀	80.2 μM Compound: 1	Cytotoxicity against Swiss mouse peritoneal macrophages after 72 hrs by AlamarBlue assay Cytotoxicity against Swiss mouse peritoneal macrophages after 72 hrs by AlamarBlue assay	[PMID: 23876028]
PWR-1E	IC₅₀	15.08 μM Compound: Quercetin	Cytotoxicity against human PWR-1E cells assessed as decrease in cell viability after 3 days by WST-1 assay Cytotoxicity against human PWR-1E cells assessed as decrease in cell viability after 3 days by WST-1 assay	[PMID: 30165345]
RAW264.7	CC₅₀	> 50 μM Compound: Quercetin	Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability after 24 hrs by MTT assay Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 26928174]
RAW264.7	IC₅₀	> 50 μM Compound: 15	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 18 hrs by griess reaction analysis Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 18 hrs by griess reaction analysis	[PMID: 24679441]
RAW264.7	IC₅₀	1.3 μM Compound: Quercetin	Inhibition of LPS-induced NO production in mouse RAW264.7 cells after 24 hrs Inhibition of LPS-induced NO production in mouse RAW264.7 cells after 24 hrs	[PMID: 23540981]
RAW264.7	IC₅₀	1.8 μM Compound: Quercetin	Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by Griess reagent based assay Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by Griess reagent based assay	[PMID: 26143931]
RAW264.7	IC₅₀	11.4 μM Compound: 9	Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced nitrite accumulation after 24 hrs by Griess reagent method Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced nitrite accumulation after 24 hrs by Griess reagent method	[PMID: 19778086]
RAW264.7	IC₅₀	15 μM Compound: Quercetin	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production by Griess assay Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production by Griess assay	[PMID: 26928174]
RAW264.7	IC₅₀	15.1 μM Compound: Quercetin	Inhibition of LPS-induced NO production in mouse RAW264.7 cells preincubated for 30 mins followed by LPS stimulation and measured after 24 hrs by Griess assay Inhibition of LPS-induced NO production in mouse RAW264.7 cells preincubated for 30 mins followed by LPS stimulation and measured after 24 hrs by Griess assay	[PMID: 32003565]
RAW264.7	IC₅₀	15.9 μM Compound: Quercetin	Inhibition of LPS-induced NO production in mouse RAW264.7 cells after 24 hrs by Griess assay Inhibition of LPS-induced NO production in mouse RAW264.7 cells after 24 hrs by Griess assay	[PMID: 27177824]
RAW264.7	IC₅₀	16.4 μM Compound: Quercetin	Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse RAW264.7 cells after 24 hrs by Griess reaction analysis Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse RAW264.7 cells after 24 hrs by Griess reaction analysis	[PMID: 23517145]
RAW264.7	IC₅₀	16.6 μM Compound: Quercetin	Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of lipopolysaccharide-induced nitric oxide production incubated for 24 hrs by Griess reagent based assay Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of lipopolysaccharide-induced nitric oxide production incubated for 24 hrs by Griess reagent based assay	[PMID: 25245917]
RAW264.7	IC₅₀	2.9 μg/mL Compound: Quercetin	Antiinflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as reduction in nitric oxide production after 24 hrs by Griess method based ELISA Antiinflammatory activity in LPS-stimulated mouse RAW264.7 cells assessed as reduction in nitric oxide production after 24 hrs by Griess method based ELISA	[PMID: 25106885]
RAW264.7	IC₅₀	22.7 μM Compound: Quercetin	Inhibition of LPS-induced NO production in mouse RAW264.7 cells by Griess reagent based assay Inhibition of LPS-induced NO production in mouse RAW264.7 cells by Griess reagent based assay	[PMID: 32118424]
RAW264.7	IC₅₀	25 μM Compound: quercetin	Inhibition of LPS and INF-alpha-induced nitric oxide production in mouse RAW264.7 cells after 16 hrs Inhibition of LPS and INF-alpha-induced nitric oxide production in mouse RAW264.7 cells after 16 hrs	[PMID: 18027905]
RAW264.7	IC₅₀	32.1 μM Compound: quercetin	Antiinflammatory activity against mouse RAW264.7 cells assessed as Inhibition of LPS-induced nitric oxide production after 24 hrs by ELISA Antiinflammatory activity against mouse RAW264.7 cells assessed as Inhibition of LPS-induced nitric oxide production after 24 hrs by ELISA	[PMID: 20121165]
RAW264.7	IC₅₀	34.5 μM Compound: Quercetin	Antiinflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as inhibition of NO production after 24 hrs Antiinflammatory activity against LPS-stimulated mouse RAW264.7 cells assessed as inhibition of NO production after 24 hrs	[PMID: 20825224]
RAW264.7	IC₅₀	4.2 μM Compound: Quercetin	Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability after 24 hrs by alamarBlue assay Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability after 24 hrs by alamarBlue assay	[PMID: 32357011]
RAW264.7	IC₅₀	4.41 μM Compound: Quercetin	Inhibition of LPS-induced NO production in mouse RAW264.7 cells preincubated for 1 hr followed by LPS stimulation measured after 24 hrs by Griess assay Inhibition of LPS-induced NO production in mouse RAW264.7 cells preincubated for 1 hr followed by LPS stimulation measured after 24 hrs by Griess assay	[PMID: 28427811]
RAW264.7	IC₅₀	4.53 μM Compound: Quercetin	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of NO production preincubated for 1 hr followed by LPS stimulation measured after 24 hrs by Griess reagent based assay Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of NO production preincubated for 1 hr followed by LPS stimulation measured after 24 hrs by Griess reagent based assay	[PMID: 32299661]
RAW264.7	IC₅₀	54.3 μM Compound: Quercetin	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production by Griess reagent method Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production by Griess reagent method	[PMID: 20056545]
RAW264.7	IC₅₀	63 μM Compound: 8	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess method Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess method	[PMID: 21353543]
RAW264.7	IC₅₀	66.6 μM Compound: 8	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNF-alpha secretion after 18 hrs Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNF-alpha secretion after 18 hrs	[PMID: 21353543]
RAW264.7	IC₅₀	9.6 μM Compound: quercetin	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess reagent assay Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess reagent assay	[PMID: 19555124]
RAW264.7	IC₅₀	95.6 μM Compound: quercetin	Cytotoxicity against mouse RAW264.7 cells after 72 hrs by MTS assay Cytotoxicity against mouse RAW264.7 cells after 72 hrs by MTS assay	[PMID: 22989363]
RF/6A	IC₅₀	40 μM Compound: Quercetin	Antimigratory activity in rhesus monkey RF/6A cells measured after 24 hrs by wound assay Antimigratory activity in rhesus monkey RF/6A cells measured after 24 hrs by wound assay	[PMID: 27015547]
RF/6A	IC₅₀	70 μM Compound: Quercetin	Antiproliferative activity in rhesus monkey RF/6A cells measured after 24 to 72 hrs by MTT assay Antiproliferative activity in rhesus monkey RF/6A cells measured after 24 to 72 hrs by MTT assay	[PMID: 27015547]
RS4-11	GI₅₀	21.6 μM Compound: 6	Cytotoxicity against human RS4:11 cells harboring wild type FLT3 after 72 hrs by tetrazolium based Ez CyTox cell viability assay Cytotoxicity against human RS4:11 cells harboring wild type FLT3 after 72 hrs by tetrazolium based Ez CyTox cell viability assay	[PMID: 23411073]
Sf21	IC₅₀	28.6 μM Compound: 5	Inhibition of human recombinant COX2 expressed in insect Sf21 cells by EIA assay Inhibition of human recombinant COX2 expressed in insect Sf21 cells by EIA assay	[PMID: 17378609]
SGC-7901	IC₅₀	7.878 μg/mL Compound: Compound 4	Cytotoxicity against human SGC7901 cells by MTT assay Cytotoxicity against human SGC7901 cells by MTT assay	[PMID: 25862199]
SK-MEL-2	IC₅₀	> 10 μM Compound: 10	Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB assay Cytotoxicity against human SK-MEL-2 cells after 48 hrs by SRB assay	[PMID: 28165740]
SK-MEL-2	IC₅₀	12 μM Compound: Quer	Cytotoxicity against human SK-MEL-2 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human SK-MEL-2 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 28654265]
SK-OV-3	IC₅₀	> 10 μM Compound: 10	Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay Cytotoxicity against human SKOV3 cells after 48 hrs by SRB assay	[PMID: 28165740]
SW1573	IC₅₀	> 10 μg/mL Compound: 8	Cytotoxicity against human SW1573 cells after 3 days by MTT assay Cytotoxicity against human SW1573 cells after 3 days by MTT assay	[PMID: 11421746]
T47D	IC₅₀	11 μM Compound: Quer	Cytotoxicity against human T47D cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human T47D cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 28654265]
U-251	IC₅₀	77.8 μM Compound: 51	Inhibition of cell proliferation of human U251 cells assessed as cell viability after 72 hrs by sulforhodamine B assay Inhibition of cell proliferation of human U251 cells assessed as cell viability after 72 hrs by sulforhodamine B assay	[PMID: 25442304]
U2OS	EC₅₀	5.93 μM Compound: Quercetin	Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactamase reporter gene assay Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactamase reporter gene assay	[PMID: 24900447]
U-87MG ATCC	IC₅₀	23 μM Compound: Quer	Cytotoxicity against human U87 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human U87 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 28654265]
Vero	IC₅₀	110 μg/mL Compound: 5	Cytotoxicity against african green monkey Vero cells by MTT assay Cytotoxicity against african green monkey Vero cells by MTT assay	[PMID: 18855442]
Vero	CC₅₀	3.32 mM Compound: 14	Cytotoxicity against african green monkey Vero cells incubated for 3 days Cytotoxicity against african green monkey Vero cells incubated for 3 days	[PMID: 32539378]
Vero C1008	CC₅₀	3.32 μM Compound: 41	Cytotoxicity against African green monkey Vero E6 cells by MTT assay Cytotoxicity against African green monkey Vero E6 cells by MTT assay	[PMID: 33486200]
WM-115	IC₅₀	177.5 μM Compound: Quercetin	Cytotoxicity against human WM115 cells after 46 hrs by MTT assay Cytotoxicity against human WM115 cells after 46 hrs by MTT assay	[PMID: 23756061]

In Vitro

Quercetin is a type of plant-based chemical, or phytochemical, used as an ingredient in supplements, beverages or foods. In several studies, it may have anti-inflammatory and antioxidant properties, and it is being investigated for a wide range of potential health benefits. Quercetin is a PI3K inhibitor with IC₅₀ of 2.4-5.4 μM. Quercetin strongly abrogates PI3K and Src kinases, mildly inhibits Akt1/2, and slightly affected PKC, p38 and ERK1/2^[1]. Quercetin inhibits TNF-induced LDH% release, EC-dependent neutrophils adhesion to bovine pulmonary artery endothelial cells (BPAEC), and BPAEC DNA synthesis and proliferation^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Combination of Quercetin (75 mg/kg) and 2-Methoxyestradiol enhances inhibition of human prostate cancer LNCaP and PC-3 cells xenograft tumor growth^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

Molecular Weight

302.24

Formula

C₁₅H₁₀O₇

CAS No.

117-39-5

Appearance

Solid

Color

Light yellow to green yellow

SMILES

OC1=C(C2=CC=C(O)C(O)=C2)OC3=CC(O)=CC(O)=C3C1=O

Structure Classification

Initial Source

Microorganisms

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	1 year
	-20°C	6 months

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (330.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Ethanol : 16.67 mg/mL (55.15 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3086 mL	16.5431 mL	33.0863 mL
5 mM	0.6617 mL	3.3086 mL	6.6173 mL
10 mM	0.3309 mL	1.6543 mL	3.3086 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (8.27 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (8.27 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 0.5% CMC-Na/saline water
Solubility: 25 mg/mL (82.72 mM); Suspended solution; Need ultrasonic
Protocol 2

Add each solvent one by one: 50% Propylene glycol 50% Saline
Solubility: 10 mg/mL (33.09 mM); Suspended solution; Need ultrasonic
Protocol 3

Add each solvent one by one: 45% PEG300 5% Tween-80 50% Saline
Solubility: 10 mg/mL (33.09 mM); Suspended solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 98.45%

Select Batch:

Data Sheet (281 KB) SDS (479 KB)

COA (250 KB) HNMR (251 KB) LCMS (95 KB)

Handling Instructions (2659 KB)

References

[1]. Leyre Navarro-Núñez, et al. Effect of quercetin on platelet spreading on collagen and fibrinogen and on multiple platelet kinases. Fitoterapia. 2010 Mar;81(2):75-80. [Content Brief]

[2]. Yu XB, et al. Inhibitory effects of protein kinase C inhibitors on tumor necrosis factor induced bovine pulmonary artery endothelial cell injuries. Yao Xue Xue Bao. 1996;31(3):176-81. [Content Brief]

[3]. Yang F, et al. Combination of Quercetin and 2-Methoxyestradiol Enhances Inhibition of Human Prostate Cancer LNCaP and PC-3 Cells Xenograft Tumor Growth. PLoS One. 2015 May 26;10(5):e0128277. [Content Brief]

[4]. Tao Liu, et al. Quercetin alleviates kidney fibrosis by reducing renal tubular epithelial cell senescence through the SIRT1/PINK1/mitophagy axis. Life Sci. 2020 Jul 20;118116. [Content Brief]

Animal Administration
^[3]

Mice are inoculated subcutaneously with 5×10⁵ PC-3 cells suspended in 100μL PBS and 2×10⁸ LNCaP cells suspended in 100μL of matrigel and PBS mixture (1:1) on the right back. When xenograft tumors reach a volume of approximately 100 mm³, mice are randomLy assigned to four groups (n=8 each group) and treated intraperitoneally. Therapeutic schedule based on our in vitro results, preliminary experiments and many other researchers' studies is as follows: (1) Vehicle control group: vehicle of quercetin on day 1, vehicle of 2-ME on day 2, (2) Quercetin treated group: quercetin 75 mg/kg on day 1, vehicle of 2-ME on day 2, (3) 2-ME treated group: vehicle of quercetin on day 1, 2-ME 150 mg/kg on day 2, (4) Combination treatment group: quercetin 75 mg/kg on day 1, 2-ME 150 mg/kg on day 2. Two days is a treatment cycle and the whole treatment process lasted for 4 weeks. Tumor sizes are monitored every 2 days using caliper and tumor volume are calculated according to the formula: L×S2×0.5, in which L represents the longest diameter and S represents the shortest diameter of tumor. Mice are weighed as well. At the end of treatment procedure, on day 29, mice are anesthetized with chloral hydrate and sacrificed by cervical dislocation. Xenograft tumors are taken out quickly and weighed. One part of it is put into liquid nitrogen immediately for future biomarker analysis and the other part is fixed in 10% neutral buffered formalin for immunohistochemical analysis. Serum biochemical parameters such as ALT, AST, creatinine and urea nitrogen that reflected drug toxicity are also detected.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References

[1]. Leyre Navarro-Núñez, et al. Effect of quercetin on platelet spreading on collagen and fibrinogen and on multiple platelet kinases. Fitoterapia. 2010 Mar;81(2):75-80. [Content Brief]

[2]. Yu XB, et al. Inhibitory effects of protein kinase C inhibitors on tumor necrosis factor induced bovine pulmonary artery endothelial cell injuries. Yao Xue Xue Bao. 1996;31(3):176-81. [Content Brief]

[3]. Yang F, et al. Combination of Quercetin and 2-Methoxyestradiol Enhances Inhibition of Human Prostate Cancer LNCaP and PC-3 Cells Xenograft Tumor Growth. PLoS One. 2015 May 26;10(5):e0128277. [Content Brief]

[4]. Tao Liu, et al. Quercetin alleviates kidney fibrosis by reducing renal tubular epithelial cell senescence through the SIRT1/PINK1/mitophagy axis. Life Sci. 2020 Jul 20;118116. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

Ethanol / DMSO	1 mM	3.3086 mL	16.5431 mL	33.0863 mL	82.7157 mL
	5 mM	0.6617 mL	3.3086 mL	6.6173 mL	16.5431 mL
	10 mM	0.3309 mL	1.6543 mL	3.3086 mL	8.2716 mL
	15 mM	0.2206 mL	1.1029 mL	2.2058 mL	5.5144 mL
	20 mM	0.1654 mL	0.8272 mL	1.6543 mL	4.1358 mL
	25 mM	0.1323 mL	0.6617 mL	1.3235 mL	3.3086 mL
	30 mM	0.1103 mL	0.5514 mL	1.1029 mL	2.7572 mL
	40 mM	0.0827 mL	0.4136 mL	0.8272 mL	2.0679 mL
	50 mM	0.0662 mL	0.3309 mL	0.6617 mL	1.6543 mL
DMSO	60 mM	0.0551 mL	0.2757 mL	0.5514 mL	1.3786 mL
	80 mM	0.0414 mL	0.2068 mL	0.4136 mL	1.0339 mL
	100 mM	0.0331 mL	0.1654 mL	0.3309 mL	0.8272 mL

Quercetin Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Quercetin117-39-5PI3KAutophagyMitophagyReactive Oxygen SpeciesApoptosisPhosphoinositide 3-kinaseMitochondrial AutophagyInhibitorinhibitorinhibit

Please select a local distributor ナミキ商事株式会社コスモ・バイオ株式会社
Product Name			Salutation
Applicant Name *			Email Address *
Phone Number *			Organization Name *
Department *			Requested quantity *
Country or Region *
Remarks

Product Name			Lot #
Applicant Name *			Email Address *
Phone Number			Department *
Organization Name *			Country or Region *
Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

Quercetin

Customer Review

Other Forms of Quercetin:

Quercetin Related Antibodies

83 Publications Citing Use of MCE Quercetin

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

View All PI3K Isoform Specific Products:

Biological Activity

Protocol

Purity & Documentation

References

Customer Review

Quercetin Related Antibodies

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

Quercetin Related Classifications

Keywords:

Your Recently Viewed Products:

Customer Review

Request for HNMR Report

SAFETY DATA SHEET (SDS)

Request for HNMR Report