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  2. Isotope-Labeled Compounds Endogenous Metabolite
  3. (R)-3-Hydroxybutanoic acid-13C4 sodium

(R)-3-Hydroxybutanoic acid-13C4 sodium  (Synonyms: (R)-(-)-3-Hydroxybutanoic acid-13C4 sodium; (R)-3-Hydroxybutyric acid-13C4 sodium)

Cat. No.: HY-W015851S2 Purity: ≥98.0%
Handling Instructions Technical Support

(R)-3-Hydroxybutanoic acid-13C4 sodium is a 13C labeled (R)-3-Hydroxybutanoic acid (HY-W051723). (R)-3-Hydroxybutanoic acid is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid can function as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones.

For research use only. We do not sell to patients.

(R)-3-Hydroxybutanoic acid-<sup>13</sup>C<sub>4</sub> sodium Chemical Structure

(R)-3-Hydroxybutanoic acid-13C4 sodium Chemical Structure

CAS No. : 2483735-72-2

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Description

(R)-3-Hydroxybutanoic acid-13C4 sodium is a 13C labeled (R)-3-Hydroxybutanoic acid (HY-W051723). (R)-3-Hydroxybutanoic acid is a metabolite converted from acetoacetic acid catalyzed by 3-hydroxybutyrate dehydrogenase. (R)-3-Hydroxybutanoic acid can function as a nutrition source, and as a precursor for vitamins, antibiotics and pheromones[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

130.06

Formula

13C4H7NaO3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[13CH3][13C@@H](O)[13CH2][13C](O[Na])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (961.09 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.6888 mL 38.4438 mL 76.8876 mL
5 mM 1.5378 mL 7.6888 mL 15.3775 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 7.6888 mL 38.4438 mL 76.8876 mL 192.2190 mL
5 mM 1.5378 mL 7.6888 mL 15.3775 mL 38.4438 mL
10 mM 0.7689 mL 3.8444 mL 7.6888 mL 19.2219 mL
15 mM 0.5126 mL 2.5629 mL 5.1258 mL 12.8146 mL
20 mM 0.3844 mL 1.9222 mL 3.8444 mL 9.6109 mL
25 mM 0.3076 mL 1.5378 mL 3.0755 mL 7.6888 mL
30 mM 0.2563 mL 1.2815 mL 2.5629 mL 6.4073 mL
40 mM 0.1922 mL 0.9611 mL 1.9222 mL 4.8055 mL
50 mM 0.1538 mL 0.7689 mL 1.5378 mL 3.8444 mL
60 mM 0.1281 mL 0.6407 mL 1.2815 mL 3.2036 mL
80 mM 0.0961 mL 0.4805 mL 0.9611 mL 2.4027 mL
100 mM 0.0769 mL 0.3844 mL 0.7689 mL 1.9222 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(R)-3-Hydroxybutanoic acid-13C4 sodium
Cat. No.:
HY-W015851S2
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