2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. (R)-CPP

(R)-CPP is a highly potent NMDA receptor antagonist.

For research use only. We do not sell to patients.

(R)-CPP Chemical Structure

(R)-CPP Chemical Structure

CAS No. : 126453-07-4

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1 mg USD 165 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of (R)-CPP:

(R)-CPP Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE (R)-CPP

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AMPA Receptor NMDA Receptor Kainate Receptor

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Description

(R)-CPP is a highly potent NMDA receptor antagonist[1].

IC50 & Target

NMDA Receptor

 

Molecular Weight

252.20

Formula

C8H17N2O5P
CAS No.
Appearance

Solid

Color

Off-white to yellow

SMILES

O=C([C@@H]1NCCN(CCCP(O)(O)=O)C1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 25.22 mg/mL (100.00 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9651 mL 19.8255 mL 39.6511 mL
5 mM 0.7930 mL 3.9651 mL 7.9302 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 98.99%

COA (244 KB) HNMR (150 KB) LCMS (416 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.9651 mL 19.8255 mL 39.6511 mL 99.1277 mL
5 mM 0.7930 mL 3.9651 mL 7.9302 mL 19.8255 mL
10 mM 0.3965 mL 1.9826 mL 3.9651 mL 9.9128 mL
15 mM 0.2643 mL 1.3217 mL 2.6434 mL 6.6085 mL
20 mM 0.1983 mL 0.9913 mL 1.9826 mL 4.9564 mL
25 mM 0.1586 mL 0.7930 mL 1.5860 mL 3.9651 mL
30 mM 0.1322 mL 0.6609 mL 1.3217 mL 3.3043 mL
40 mM 0.0991 mL 0.4956 mL 0.9913 mL 2.4782 mL
50 mM 0.0793 mL 0.3965 mL 0.7930 mL 1.9826 mL
60 mM 0.0661 mL 0.3304 mL 0.6609 mL 1.6521 mL
80 mM 0.0496 mL 0.2478 mL 0.4956 mL 1.2391 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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(R)-CPP Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R)-CPP126453-07-4iGluRIonotropic glutamate receptorsInhibitorinhibitorinhibit

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