(RS)-CPP (Synonyms: (±)-CPP)

Name: (RS)-CPP
Brand: MedChemExpress
SKU: HY-100797
Rating: 4.5 (1 reviews)

Cat. No.: HY-100797 Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

(RS)-CPP ((±)-CPP) is a potent and selective NMDA antagonist. (RS)-CPP inhibits central neuron responses, and has anticonvulsant activity.

For research use only. We do not sell to patients.

(RS)-CPP Chemical Structure

CAS No. : 100828-16-8

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	Get quote
10 mg	Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of (RS)-CPP:

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Description

(RS)-CPP ((±)-CPP) is a potent and selective NMDA antagonist. (RS)-CPP inhibits central neuron responses, and has anticonvulsant activity^[1].

Molecular Weight

252.20

Formula

C₈H₁₇N₂O₅P

CAS No.

100828-16-8

Appearance

Solid

Color

White to light brown

SMILES

O=C(C1NCCN(CCCP(O)(O)=O)C1)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 99.2 mg/mL (393.34 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.9651 mL	19.8255 mL	39.6511 mL
5 mM	0.7930 mL	3.9651 mL	7.9302 mL
10 mM	0.3965 mL	1.9826 mL	3.9651 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (266 KB) SDS (252 KB)

COA (244 KB)

Handling Instructions (2659 KB)

References

[1]. J Davies, et al. CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]D-AP5 binding sites on brain membranes and anticonvulsant activity. Brain Res. 1986 Sep 10;382(1):169-73. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	3.9651 mL	19.8255 mL	39.6511 mL	99.1277 mL
	5 mM	0.7930 mL	3.9651 mL	7.9302 mL	19.8255 mL
	10 mM	0.3965 mL	1.9826 mL	3.9651 mL	9.9128 mL
	15 mM	0.2643 mL	1.3217 mL	2.6434 mL	6.6085 mL
	20 mM	0.1983 mL	0.9913 mL	1.9826 mL	4.9564 mL
	25 mM	0.1586 mL	0.7930 mL	1.5860 mL	3.9651 mL
	30 mM	0.1322 mL	0.6609 mL	1.3217 mL	3.3043 mL
	40 mM	0.0991 mL	0.4956 mL	0.9913 mL	2.4782 mL
	50 mM	0.0793 mL	0.3965 mL	0.7930 mL	1.9826 mL
	60 mM	0.0661 mL	0.3304 mL	0.6609 mL	1.6521 mL
	80 mM	0.0496 mL	0.2478 mL	0.4956 mL	1.2391 mL
	100 mM	0.0397 mL	0.1983 mL	0.3965 mL	0.9913 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

(RS)-CPP Related Classifications

Neurological Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(RS)-CPP100828-16-8(±)-CPPiGluRIonotropic glutamate receptorsNMDA antagonistD-AP5entral neuron responsesanticonvulsant activityInhibitorinhibitorinhibit

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(RS)-CPP (Synonyms: (±)-CPP)

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Complete Stock Solution Preparation Table

(RS)-CPP Related Classifications

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