(rac)-3-O-Methyl DOPA-d₃

Name: (rac)-3-O-Methyl DOPA-d 3
Brand: MedChemExpress
SKU: HY-132404S
Rating: 4.5 (1 reviews)

Cat. No.: HY-132404S Purity: 98.73%: FAQs
Data Sheet SDS COA Handling Instructions

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(rac)-3-O-Methyl DOPA-d₃ is the deuterium labeled (rac)-3-O-Methyl DOPA[1].

For research use only. We do not sell to patients.

(rac)-3-O-Methyl DOPA-d<sub>3</sub> Chemical Structure

(rac)-3-O-Methyl DOPA-d₃ Chemical Structure

CAS No. : 1219173-95-1

Size	Price	Stock	Quantity
1 mg	USD 260	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 920	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of (rac)-3-O-Methyl DOPA-d₃:

3-O-Methyldopa-d₃ In-stock
3-O-Methyldopa-d₃ hydrate Get quote

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Description

(rac)-3-O-Methyl DOPA-d₃ is the deuterium labeled (rac)-3-O-Methyl DOPA[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

214.23

Formula

C₁₀H₁₀D₃NO₄

CAS No.

1219173-95-1

Unlabeled CAS

7636-26-2

Appearance

Solid

Color

Off-white to light yellow

SMILES

C(C(C(O)=O)N)C1=CC(OC([2H])([2H])[2H])=C(O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 25 mg/mL (116.70 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.6679 mL	23.3394 mL	46.6788 mL
5 mM	0.9336 mL	4.6679 mL	9.3358 mL
10 mM	0.4668 mL	2.3339 mL	4.6679 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

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In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.73%

Select Batch:

Data Sheet (270 KB) SDS (393 KB)

COA (246 KB) HNMR (142 KB) RP-HPLC (164 KB) LCMS (107 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	4.6679 mL	23.3394 mL	46.6788 mL	116.6970 mL
	5 mM	0.9336 mL	4.6679 mL	9.3358 mL	23.3394 mL
	10 mM	0.4668 mL	2.3339 mL	4.6679 mL	11.6697 mL
	15 mM	0.3112 mL	1.5560 mL	3.1119 mL	7.7798 mL
	20 mM	0.2334 mL	1.1670 mL	2.3339 mL	5.8349 mL
	25 mM	0.1867 mL	0.9336 mL	1.8672 mL	4.6679 mL
	30 mM	0.1556 mL	0.7780 mL	1.5560 mL	3.8899 mL
	40 mM	0.1167 mL	0.5835 mL	1.1670 mL	2.9174 mL
	50 mM	0.0934 mL	0.4668 mL	0.9336 mL	2.3339 mL
	60 mM	0.0778 mL	0.3890 mL	0.7780 mL	1.9450 mL
	80 mM	0.0583 mL	0.2917 mL	0.5835 mL	1.4587 mL
	100 mM	0.0467 mL	0.2334 mL	0.4668 mL	1.1670 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.