2. TGF-beta/Smad
  3. TGF-β Receptor
  4. Ramatercept

Ramatercept  (Synonyms: ACE-031)

Cat. No.: HY-P99818

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Ramatercept (ACE-031) is a soluble ActRIIB receptor and can be used as a soluble activin receptor 2 (ACVR2) antagonist. Ramatercept inhibits the signal pathway of muscle growth inhibition and has potential application in muscle atrophy.

For research use only. We do not sell to patients.

CAS No. : 1169766-01-1

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Ramatercept Related Antibodies

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ALK1 ALK2 ALK3 ALK4 ALK5 ALK6 ALK7 TGFβR2 ACVR2A ACVR2B

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Description

Ramatercept (ACE-031) is a soluble ActRIIB receptor and can be used as a soluble activin receptor 2 (ACVR2) antagonist. Ramatercept inhibits the signal pathway of muscle growth inhibition and has potential application in muscle atrophy[1][2][3].

IC50 & Target

soluble activin receptor 2, ACVR2[2]
In Vivo

Ramatercept (ACE-031) (10 mg/kg; s.c.; three times a week for 5 weeks) significantly increases the muscle mass of mice[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
CAS No.
SMILES

[Ramatercept]
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • [ACVR2B (activin A receptor type 2B, ActR-IIB, ActRIIB)]2-IGHG1 Fc (Fragment constant)
Purity & Documentation
References
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Ramatercept Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ramatercept1169766-01-1ACE-031ACE031ACE 031TGF-β ReceptorTransforming growth factor beta receptorsMuscle atrophyInhibitorinhibitorinhibit

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