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Ranevetmab (NV-01) is a caninised anti-NGF monoclonal antibody (mAb). Ranevetmab can alleviate pain, and is used for the research of degenerative joint disease (DJD) pain.

For research use only. We do not sell to patients.

CAS No. : 1632282-27-9

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Description

Ranevetmab (NV-01) is a caninised anti-NGF monoclonal antibody (mAb). Ranevetmab can alleviate pain, and is used for the research of degenerative joint disease (DJD) pain[1].

Isotype

Canis IgG1 kappa

Species

Caninized

IC50 & Target[1]

NGF

 

In Vivo

Ranevetmab (200 μg/kg, i.v.) alleviates degenerative joint disease (DJD) pain in dogs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Dogs with degenerative joint disease (DJD) pain[2]
Dosage: 200 μg/kg
Administration: i.v.
Result: Improved canine brief pain inventory (CBPI), pain severity (PS) and pain interference (PI) scores.
CAS No.
SMILES

[Ranevetmab]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • IgG1-kappa
Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ranevetmab
Cat. No.:
HY-P99820
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