2. Metabolic Enzyme/Protease
  3. Phosphatase
  4. Rbin-2

Rbin-2 is a potent, reversible and selective inhibitor of Midasin (Mdn1), an enzyme belonging to the AAA+ (ATPases associated with diverse cellular activities) protein family. Rbin-2 inhibits eukaryotic ribosome biogenesis and is a powerful probe for the eukaryotic ribosome assembly.

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Rbin-2 Chemical Structure

Rbin-2 Chemical Structure

CAS No. : 2032282-97-4

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5 mg USD 110 In-stock
10 mg USD 190 In-stock
25 mg USD 420 In-stock
50 mg USD 670 In-stock
100 mg USD 1070 In-stock
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Based on 1 publication(s) in Google Scholar

Rbin-2 Related Antibodies

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Description

Rbin-2 is a potent, reversible and selective inhibitor of Midasin (Mdn1), an enzyme belonging to the AAA+ (ATPases associated with diverse cellular activities) protein family. Rbin-2 inhibits eukaryotic ribosome biogenesis and is a powerful probe for the eukaryotic ribosome assembly[1].

Molecular Weight

335.22

Formula

C13H11BrN4S
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

C=C(C)CSC1=NN=C2C(NC3=C2C=CC(Br)=C3)=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 8.33 mg/mL (24.85 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9831 mL 14.9156 mL 29.8312 mL
5 mM 0.5966 mL 2.9831 mL 5.9662 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9831 mL 14.9156 mL 29.8312 mL 74.5779 mL
5 mM 0.5966 mL 2.9831 mL 5.9662 mL 14.9156 mL
10 mM 0.2983 mL 1.4916 mL 2.9831 mL 7.4578 mL
15 mM 0.1989 mL 0.9944 mL 1.9887 mL 4.9719 mL
20 mM 0.1492 mL 0.7458 mL 1.4916 mL 3.7289 mL
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Rbin-2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rbin-22032282-97-4Rbin2Rbin 2PhosphataseInhibitorinhibitorinhibit

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