Acylphosphatase-2/ACYP2 Protein, Human (GST)

Acylphosphatase-2/ACYP2 Protein, Human (GST) is human recombinant Acylphosphatase-2 (ACYP2) with a GST tag at the N-terminus. Acylphosphatase-2/ACYP2 Protein, Human (GST) is produced by E.coli and the target gene encoding Ser2-Tyr99 is expressed.

Acylphosphatase-2 (ACYP2) is a small cytosolic acylphosphatase enzyme. The ACYP2 gene, located on chromosome 2p16.2, catalyzes the hydrolysis of carboxyl-phosphate bonds and hydrolyzes the phosphoenzyme intermediates of various membrane pumps, such as the sarcoplasmic reticulum Ca²⁺/Mg²⁺-ATPase found in skeletal muscle^[1].

Human

E. coli

N-GST

P14621 (S2-Y99)

98  [NCBI]

MSPILGYWKIKGLVQPTRLLLEYLEEKYEEHLYERDEGDKWRNKKFELGLEFPNLPYYIDGDVKLTQSMAIIRYIADKHNMLGGCPKERAEISMLEGAVLDIRYGVSRIAYSKDFETLKVDFLSKLPEMLKMFEDRLCHKTYLNGDHVTHPDFMLYDALDVVLYMDPMCLDAFPKLVCFKKRIEAIPQIDKYLKSSKYIAWPLQGWQATFGGGDHPPKSTAQSLKSVDYEVFGRVQGVCFRMYTEDEARKIGVVGWVKNTSKGTVTGQVQGPEDKVNSMKSWLSKVGSPSSRIDRTNFSNEKTISKLEYSNFSIRY

Approximately 34.0 kDa

Greater than 80% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.

• [1]. Wu J, et al. Single Nucleotide Polymorphisms in the Acylphosphatase 2 Gene and The SNP-SNP Interactions on the Risk of Breast Cancer in Chinese Han Women. Clin Breast Cancer. 2018 Jun;18(3):e329-e333.  [Content Brief]