2. Gene
  3. ACYP2 - acylphosphatase 2 Gene

ACYP2 - acylphosphatase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as ACYM; ACYP

Gene ID: 98 | Gene type: protein coding

About ACYP2

Cytogenetic location: 2p16.2 Genomic coordinates (GRCh38): 2:53,971,113-54,305,300 (from NCBI)

This gene has 9 transcripts (splice variants), 238 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 3.1), heart (RPKM 2.8) and 25 other tissues.

Summary

Acylphosphatase can hydrolyze the phosphoenzyme intermediate of different membrane pumps, particularly the Ca2+/Mg2+-ATPase from sarcoplasmic reticulum of skeletal muscle. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase on the basis of their tissue localization. This gene encodes the muscle-type isoform (MT). An increase of the MT isoform is associated with muscle differentiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

ACYP2 Products(6)

mRNA Protein Name
NM_001320586.2 NP_001307515.1 acylphosphatase-2 isoform 1
NM_001320587.2 NP_001307516.1 acylphosphatase-2 isoform 2
NM_001320588.2 NP_001307517.1 acylphosphatase-2 isoform 4
NM_001320589.2 NP_001307518.1 acylphosphatase-2 isoform 5
NM_001320590.2 NP_001307519.1 acylphosphatase-2 isoform 6
NM_138448.4 NP_612457.1 acylphosphatase-2 isoform 3
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
12374855 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ACYP2 Protein Structure

Acylphosphatase

Acylphosphatase: Acylphosphatase (8 - 98)

  • 0
  • 99 a.a.
Protein Preferred Names Protein Names

acylphosphatase-2

acylphosphatase 2, muscle type

Recombinant ACYP2 Proteins

Cat. No. Product Name Accession Purity
HY-P7459 Acylphosphatase-2/ACYP2 Protein, Human (GST) P14621 (S2-Y99) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00257 ACYP2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus ACYP2 VGNC VGNC:98504
Mus musculus ACYP2 MGD MGI:1922822
Rattus norvegicus ACYP2 RGD RGD:1595836
Canis familiaris ACYP2 VGNC VGNC:37567
Macaca mulatta ACYP2 VGNC VGNC:82096
Bos taurus ACYP2 VGNC VGNC:25599
Others ACYP2 NCBI