Aminopeptidase N/APN Protein, Mouse (HEK293, His)

Aminopeptidase N/APN proteins act as aminopeptidases with broad specificity, assisting in the final stages of peptide digestion and processing of various peptides, including the hormones angiotensin III/IV and neuropeptides.Aminopeptidase N/APN Protein, Mouse (HEK293, His) is the recombinant mouse-derived Aminopeptidase N/APN protein, expressed by HEK293 , with C-6*His labeled tag.

Aminopeptidase N/APN Protein exhibits broad specificity as an aminopeptidase, contributing to the final stages of peptide digestion arising from the hydrolysis of proteins by gastric and pancreatic proteases. Beyond its digestive role, it participates in the processing of various peptides, including peptide hormones like angiotensin III and IV, neuropeptides, and chemokines. Additionally, it is implicated in the cleavage of peptides bound to major histocompatibility complex class II molecules on antigen-presenting cells. Aminopeptidase N/APN may play a role in angiogenesis, cholesterol crystallization promotion, and potentially acts as a binding partner for amino acid transporter SLC6A19, thereby regulating its activity and influencing amino acid transport.

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Mouse

HEK293

C-6*His

P97449 (K69-S966)

16790  [NCBI]

KPWNQYRLPKTLIPDSYRVILRPYLTPNNQGLYIFQGNSTVRFTCNQTTDVIIIHSKKLNYTLKGNHRVVLRTLDGTPAPNIDKTELVERTEYLVVHLQGSLVEGRQYEMDSQFQGELADDLAGFYRSEYMEGDVKKVVATTQMQAADARKSFPCFDEPAMKAMFNITLIYPNNLIALSNMLPKESKPYPEDPSCTMTEFHSTPKMSTYLLAYIVSEFKNISSVSANGVQIGIWARPSAIDEGQGDYALNVTGPILNFFAQHYNTSYPLPKSDQIALPDFNAGAMENWGLVTYRESSLVFDSQSSSISNKERVVTVIAHELAHQWFGNLVTVAWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSSPADEIKTPDQIMELFDSITYSKGASVIRMLSSFLTEDLFKKGLSSYLHTYQYSNTVYLDLWEHLQKAVNQQTAVQPPATVRTIMDRWILQMGFPVITVNTNTGEISQKHFLLDSKSNVTRPSEFNYIWIAPIPFLKSGQEDHYWLDVEKNQSAKFQTSSNEWILLNINVTGYYLVNYDENNWKKLQNQLQTDLSVIPVINRAQIIHDSFNLASAKMIPITLALDNTLFLVKEAEYMPWQAALSSLNYFTLMFDRSEVYGPMKRYLKKQVTPLFFYFQNRTNNWVNRPPTLMEQYNEINAISTACSSGLKECRDLVVELYSQWMKNPNNNTIHPNLRSTVYCNAIAFGGEEEWNFAWEQFRNATLVNEADKLRSALACSKDVWILNRYLSYTLNPDYIRKQDTTSTIISIASNVAGHPLVWDFVRSNWKKLFENYGGGSFSFANLIQGVTRRFSSEFELQQLEQFKADNSATGFGTGTRALEQALEKTRANIDWVKENKDAVFKWFTENSS

110-130 kDa

Greater than 95% as determined by reducing SDS-PAGE

Solution.

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

N/A

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.