B7-1/CD80 Protein, Mouse (Biotinylated, HEK293, His)

B7-1/CD80 Protein, crucial in activating T lymphocytes, engages CD28 or CTLA-4 receptors, inducing proliferation and cytokine production. This interaction regulates immune responses and influences T lymphocyte activation and function. Serving as a key checkpoint, B7-1/CD80 orchestrates signaling events, controlling the immune system's dynamic responses. B7-1/CD80 Protein, Mouse (Biotinylated, HEK293, His) is the recombinant mouse-derived B7-1/CD80 protein, expressed by HEK293 , with C-His labeled tag.

B7-1/CD80 Protein plays a pivotal role in the costimulatory signal necessary for the activation of T lymphocytes. Its engagement with CD28 or CTLA-4 receptors is integral to inducing T-cell proliferation and cytokine production. The interaction between B7-1/CD80 and these receptors orchestrates critical signaling events that regulate immune responses, influencing the activation and function of T lymphocytes. This molecular interaction serves as a key checkpoint in the complex network of cellular signals governing the immune system's dynamic responses.

Mouse

HEK293

C-His

Q00609 (V38-K245)

12519  [NCBI]

Approximately 25.1 kDa.

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.