CD21 Protein, Mouse (HEK293, His)

CD21 protein, as a receptor for complement C3d and HNRNPU, plays a crucial role in B lymphocyte activation. It forms complexes with CD19, CR2/CD21, CD81 and IFITM1/CD225 and contributes to immune responses. CD21 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD21 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD21 Protein, Mouse (HEK293, His) is 952 a.a., with molecular weight of 130-150 kDa.

CD21 Protein, functioning as a receptor for complement C3d and HNRNPU, is integral to the activation of B lymphocytes. Through interactions with C3 and CD19, CD21 participates in immune responses and forms part of a complex that includes CD19, CR2/CD21, CD81, and IFITM1/CD225 in the membrane of mature B-cells. The intricate network of interactions, specifically via Sushi domains 1 and 2, emphasizes CD21's role in modulating immune signaling. Additionally, CD21 associates with FCER2, specifically through the C-terminus, highlighting its involvement in various cellular processes and underscoring its significance in B-cell activation and immune regulation.

Mouse

HEK293

C-His

P19070 (I12-W963)

12902  [NCBI]

130-150 kDa

Greater than 95% as determined by Tris-Bis PAGE

<1 EU/μg, determined by LAL method.