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  4. CD24/Heat-stable Antigen
  5. CD24 Protein, Mouse (27a.a, HEK293, mFc)

The CD24 protein may coordinate cellular differentiation of various cell types, particularly in early thymocyte development. Activation of its signaling involves binding of a lectin-like ligand to the CD24 carbohydrate, triggering the release of second messengers from GPI anchors. CD24 Protein, Mouse (27a.a, HEK293, mFc) is the recombinant mouse-derived CD24 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of CD24 Protein, Mouse (27a.a, HEK293, mFc) is 27 a.a., with molecular weight of 58-62 kDa.

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Description

The CD24 protein may coordinate cellular differentiation of various cell types, particularly in early thymocyte development. Activation of its signaling involves binding of a lectin-like ligand to the CD24 carbohydrate, triggering the release of second messengers from GPI anchors. CD24 Protein, Mouse (27a.a, HEK293, mFc) is the recombinant mouse-derived CD24 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of CD24 Protein, Mouse (27a.a, HEK293, mFc) is 27 a.a., with molecular weight of 58-62 kDa.

Background

CD24 Protein is postulated to play a pivotal role in the cell differentiation processes of various cell types, with a specific implication in early thymocyte development. Its signaling potential is suggested to be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, transduced through the release of second messengers derived from the GPI-anchor. Additionally, CD24 is implicated in modulating B-cell activation responses, indicative of its regulatory influence in immune processes. In conjunction with SIGLEC10, CD24 may participate in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70, and HSP90. This CD24:SIGLEC10 complex is proposed to inhibit HMGB1-mediated tissue damage immune responses, suggesting CD24's role in immune regulation and control of autoimmunity. The multifaceted functions of CD24 underscore its potential as a key player in diverse cellular and immune processes.

Species

Mouse

Source

HEK293

Tag

C-mFc

Accession

P24807 (N27-G53)

Gene ID
Molecular Construction
N-term
CD24 (N27-G53)
Accession # P24807
mFc
C-term
Synonyms
CD 24; CD24 molecule; CD24A; FLJ22950; FLJ43543; MGC75043
Molecular Weight

58-62 kDa

Purity

Greater than 95% as determined by Tris-Bis PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
CD24 Protein, Mouse (27a.a, HEK293, mFc)
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HY-P78255
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