CD28 Protein, Mouse (Biotinylated , HEK293, His)

CD28 Protein, a crucial regulator of T-cell activation, promotes cell proliferation, cytokine production, and T-cell survival. It enhances IL4 and IL10 production when combined with TCR/CD3 ligation and CD40L costimulation. CD28 Protein exists as a disulfide-linked homodimer and interacts with DUSP14, CD80/B7-1, CD86/B7-2/B70, and GRB2 (By similarity). CD28 Protein, Mouse (Biotinylated, HEK293, His) is the recombinant mouse-derived CD28 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD28 Protein, Mouse (Biotinylated, HEK293, His) is 130 a.a., with molecular weight of 32-35 kDa.

CD28 Protein, a key player in T-cell activation, is involved in inducing cell proliferation, cytokine production, and promoting T-cell survival. It enhances the production of IL4 and IL10 in T-cells when combined with TCR/CD3 ligation and CD40L costimulation. CD28 Protein exists as a homodimer through disulfide-linkage and interacts with DUSP14. It binds to CD80/B7-1 and CD86/B7-2/B70, and also has an interaction with GRB2 (By similarity).

Mouse

HEK293

C-His

P31041 (N20-K149)

12487  [NCBI]

32-35 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.