CD38 Protein, Mouse (HEK293, His)

CD38 protein is pivotal in synthesizing crucial second messengers, cyclic ADP-ribose (cADPR) and nicotinate-adenine dinucleotide phosphate (NAADP). cADPR participates in glucose-induced insulin secretion, and NAADP functions as a calcium mobilizer. CD38 also displays cADPR hydrolase activity, showcasing its multifunctionality. CD38 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD38 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CD38 Protein, Mouse (HEK293, His) is 260 a.a., with molecular weight of 38-47 kDa.

The CD38 protein plays a crucial role in synthesizing two important second messengers: cyclic ADP-ribose (cADPR) and nicotinate-adenine dinucleotide phosphate (NAADP). cADPR acts as a second messenger involved in glucose-induced insulin secretion, while NAADP serves as a calcium mobilizer. Additionally, CD38 exhibits cADPR hydrolase activity, further contributing to its functional versatility.

Mouse

HEK293

C-6*His

P56528 (L45-T304)

12494  [NCBI]

LRPRSLLVWTGEPTTKHFSDIFLGRCLIYTQILRPEMRDQNCQEILSTFKGAFVSKNPCNITREDYAPLVKLVTQTIPCNKTLFWSKSKHLAHQYTWIQGKMFTLEDTLLGYIADDLRWCGDPSTSDMNYVSCPHWSENCPNNPITVFWKVISQKFAEDACGVVQVMLNGSLREPFYKNSTFGSVEVFSLDPNKVHKLQAWVMHDIEGASSNACSSSSLNELKMIVQKRNMIFACVDNYRPARFLQCVKNPEHPSCRLNT

38-47 kDa

Greater than 95% as determined by reducing SDS-PAGE.

Solution.

Supplied as a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.