CDCP1 Protein, Human (312a.a, HEK293, His)

CDCP1 protein may be involved in cell adhesion and extracellular matrix association. Phosphorylation of CDCP1 may regulate the balance between anchorage and migration, proliferation, and differentiation. CDCP1 Protein, Human (312a.a, HEK293, His) is the recombinant human-derived CDCP1 protein, expressed by HEK293 , with C-6*His labeled tag.

CDCP1 protein is potentially involved in cell adhesion and the association with the extracellular matrix. Its phosphorylation may play a role in regulating the balance between anchorage and migration, as well as proliferation and differentiation. Additionally, CDCP1 has shown promise as a novel marker for leukemia diagnosis and for identifying immature hematopoietic stem cell subsets. It belongs to the tetraspanin web, which is implicated in tumor progression and metastasis. CDCP1 interacts with several proteins including CDH2/N-cadherin, CDH3/P-cadherin, SDC1/syndecan-1, SDC4/syndecan-4, the serine protease ST14/MT-SP1, as well as SRC and PRKCG/protein kinase C gamma, suggesting its involvement in various cellular processes and signaling pathways.

Human

HEK293

C-6*His

Q9H5V8-3 (F30-S341)

64866  [NCBI]

FEIALPRESNITVLIKLGTPTLLAKPCYIVISKRHITMLSIKSGERIVFTFSCQSPENHFVIEIQKNIDCMSGPCPFGEVQLQPSTSLLPTLNRTFIWDVKAHKSIGLELQFSIPRLRQIGPGESCPDGVTHSISGRIDATVVRIGTFCSNGTVSRIKMQEGVKMALHLPWFHPRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANYPEGFPEDELMTWQFVVPAHLRASVSFLNFNLSNCERKEERVEYYIPGSTTNPEVFKLEDKQPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQHPQNES

Approximately 55.0 kDa

Greater than 90% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.