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  3. Cerberus 1/CER1 Protein, Human (sf9, His)

Cerberus 1/CER1 Protein, Human (sf9, His)

Cat. No.: HY-P75350
Handling Instructions

The Cerberus 1/CER1 protein emerges as a cytokine that may be involved in preneural induction and somite formation during embryogenesis, in part through its inhibitory effect on BMP signaling. Its regulatory role extends into gastrulation, where it can influence nodal signaling and contribute to primitive streak formation and patterning. Cerberus 1/CER1 Protein, Human (sf9, His) is the recombinant human-derived Cerberus 1/CER1 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Cerberus 1/CER1 Protein, Human (sf9, His) is 267 a.a., with molecular weight of ~29.6 kDa.

For research use only. We do not sell to patients.

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Description

The Cerberus 1/CER1 protein emerges as a cytokine that may be involved in preneural induction and somite formation during embryogenesis, in part through its inhibitory effect on BMP signaling. Its regulatory role extends into gastrulation, where it can influence nodal signaling and contribute to primitive streak formation and patterning. Cerberus 1/CER1 Protein, Human (sf9, His) is the recombinant human-derived Cerberus 1/CER1 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Cerberus 1/CER1 Protein, Human (sf9, His) is 267 a.a., with molecular weight of ~29.6 kDa.

Background

Cerberus 1 (CER1) is a cytokine with potential significance in embryonic development, particularly in anterior neural induction and somite formation. Its involvement is attributed, at least in part, to its inhibitory action on BMP (bone morphogenetic protein). CER1 exhibits a regulatory role in Nodal signaling during gastrulation and contributes to the formation and patterning of the primitive streak, suggesting its multifaceted influence on early developmental processes. Structurally, CER1 is known to form monomers and predominantly exists as dimers, indicating its dynamic molecular organization. The ability of CER1 to modulate key signaling pathways and participate in embryogenesis underscores its importance in orchestrating complex developmental events.

Species

Human

Source

Sf9 insect cells

Tag

C-His

Accession

O95813 (M1-A267)

Gene ID
Molecular Construction
N-term
CER1 (M1-A267)
Accession # O95813
His
C-term
Synonyms
Cerberus; DAN domain family member 4; CER1; DAND4
Molecular Weight

Approximately 29.6 kDa

Purity

Greater than 80% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

Cerberus 1/CER1 Protein, Human (sf9, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Cerberus 1/CER1 Protein, Human (sf9, His)
Cat. No.:
HY-P75350
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