2. Gene
  3. CER1 - cerberus 1, DAN family BMP antagonist Gene

CER1 - cerberus 1, DAN family BMP antagonist Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as DAND4

Gene ID: 9350 | Gene type: protein coding

About CER1

Cytogenetic location: 9p22.3 Genomic coordinates (GRCh38): 9:14,717,326-14,722,733 (from NCBI)

This gene has 1 transcript (splice variant), 125 orthologues and 1 paralogue. Low expression observed in reference dataset.

Summary

This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. [provided by RefSeq, Jul 2008]

CER1 Products(1)

mRNA Protein Name
NM_005454.3 NP_005445.1 cerberus precursor

CER1 Protein Structure

DAN

DAN: DAN domain (133 - 246)

  • 0
  • 100
  • 200
  • 267 a.a.
Protein Preferred Names Protein Names

cerberus

DAN domain family member 4

Recombinant CER1 Proteins

Cat. No. Product Name Accession Purity
HY-P7822 Cerberus 1/CER1 Protein, Human (HEK293, His) AAI03977.1 (T18-A267) ≥95%
HY-P75350 Cerberus 1/CER1 Protein, Human (sf9, His) O95813 (M1-A267) ≥95%

Related Diseases

Diseases Alias
Chromosome 9p Deletion Syndrome

Monosomy 9p

Monosomy 9p Syndrome

Alfi Syndrome

9p Syndrome

Chromosome 9p Deletion

9p Deletion

9p Monosomy

Deletion 9p

Partial Monosomy 9p

9p Deletion Syndrome

9p- Syndrome

Alfi'S Syndrome

Chromosome 9, Partial Trisomy 9p
Cardiomyopathy, Dilated, 1x

Dilated Cardiomyopathy 1x

CMD1X

Dilated Cardiomyopathy With Mild Or No Proximal Muscle Weakness

Cardiomyopathy, Dilated, With Mild Or No Proximal Muscle Weakness

Cardiomyopathy, Dilated 1x

Cardiomyopathy, Dilated, Type 1x
Anisometropia
Kleefstra Syndrome 1

9q Subtelomeric Deletion Syndrome

KLEFS1

Chromosome 9q34.3 Deletion Syndrome

9q- Syndrome

9q34 Deletion Syndrome

Kleefstra Syndrome Due To 9q34 Microdeletion

Kleefstra Syndrome

9q-Syndrome

9qstds

Kleefstra Syndrome Due To 9q Subtelomeric Deletion

Kleefstra Syndrome Due To Del(9)(Q34)

Kleefstra Syndrome Due To Monosomy 9q34

Chromosome 9q Subtelomeric Deletion Syndrome

Kleefstra Syndrome, Type 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-126015 P053 Inhibitor ≥97.0% Unkown
HY-120803 Mefluidide / Unkown
HY-146910S CER1 (d18:1/26:0/18:1)-d9 / Unkown
HY-RS02532 CER1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS02536 CERS1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus CER1 MGD MGI:1201414
Bos taurus CER1 VGNC VGNC:27221
Rattus norvegicus CER1 RGD RGD:1563046
Felis catus CER1 VGNC VGNC:102913
Macaca mulatta CER1 VGNC VGNC:71011
Canis familiaris CER1 VGNC VGNC:39145
Others CER1 NCBI