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  4. CKAP4 Protein, Human (His)

CKAP4 Protein, Human (His)

Cat. No.: HY-P700976
Handling Instructions

For research use only. We do not sell to patients.

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Top Publications Citing Use of Products

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Background

CKAP1/TBCB Protein assumes a crucial role in cellular functions by mediating the anchoring of the endoplasmic reticulum to microtubules, contributing to the structural organization of the cell. Additionally, it functions as a high-affinity epithelial cell surface receptor for the low molecular weight sialoglycopeptide APF/antiproliferative factor, playing a pivotal role in transducing APF's antiproliferative signaling within cells. This dual functionality underscores CKAP1/TBCB's significance in both intracellular structural dynamics, through its involvement in endoplasmic reticulum anchoring, and cellular signaling processes, as an essential mediator of APF-induced antiproliferative effects at the cell surface.
Species

Human
Source

E. coli
Tag

N-His
Accession

Q07065 (H128-V602)
Gene ID
Molecular Construction
N-term
His
CKAP4 (H128-V602)
Accession # Q07065
C-term
Synonyms
Climp-63; p63; CLIMP-63; ERGIC-63;
Molecular Weight

53.66 kDa
Purity

Greater than 90 % as determined by SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

CKAP4 Protein, Human (His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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