Eotaxin/CCL11 Protein, Human (His)

Eotaxin/CCL11 Protein actively promotes eosinophil accumulation in response to allergens, a distinctive feature of allergic inflammation, emphasizing its pivotal role in immune response orchestration during allergies. This regulatory function is achieved through binding to the CCR3 receptor, underscoring its specific interaction with cellular receptors to modulate eosinophil migration and activation in response to allergenic stimuli. Eotaxin/CCL11 Protein, Human (His) is the recombinant human-derived Eotaxin/CCL11 protein, expressed by E. coli , with N-His labeled tag. The total length of Eotaxin/CCL11 Protein, Human (His) is 74 a.a., with molecular weight of 13-15 kDa.

In response to the presence of allergens, the Eotaxin/CCL11 protein actively facilitates the accumulation of eosinophils, a distinctive hallmark of allergic inflammatory reactions. This effect is well-documented in scientific literature, underscoring the protein's pivotal role in orchestrating immune responses during allergic processes. Notably, Eotaxin/CCL11 achieves this regulatory function by binding to the CCR3 receptor, highlighting its specific interaction with cellular receptors to modulate the migration and activation of eosinophils in response to allergenic stimuli.

Human

E. coli

N-His

P51671 (G24-P97)

6356  [NCBI]

13-15 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.