Glypican-5/GPC5 Protein, Human (sf9, His)

Glypican-5 (GPC5) protein is a cell surface proteoglycan characterized by specific binding to heparan sulfate. As a proteoglycan, GPC5 consists of a core protein covalently linked to heparan sulfate chains. Glypican-5/GPC5 Protein, Human (sf9, His) is the recombinant human-derived Glypican-5/GPC5 protein, expressed by Sf9 insect cells , with C-His labeled tag.

Glypican-5 (GPC5) protein is a cell surface proteoglycan that is distinguished by its specific association with heparan sulfate. As a proteoglycan, GPC5 consists of a core protein that is covalently attached to heparan sulfate chains. The presence of this protein on the cell surface suggests its involvement in cellular signaling and communication. Heparan sulfate chains, which are known for their ability to interact with various growth factors and other signaling molecules, likely contribute to GPC5's role in modulating signaling pathways and cellular processes. The unique characteristics of GPC5, including its association with heparan sulfate, suggest its significant contribution to cellular functions and highlight its potential as a target for further research and therapeutic interventions.

Human

Sf9 insect cells

C-His

P78333/NP_004457.1 (E25-T554)

2262  [NCBI]

MDAQTWPVGFRCLLLLALVGSARSEGVQTCEEVRKLFQWRLLGAVRGLPDSPRAGPDLQVCISKKPTCCTRKMEERYQIAARQDMQQFLQTSSSTLKFLISRNAAAFQETLETLIKQAENYTSILFCSTYRNMALEAAASVQEFFTDVGLYLFGADVNPEEFVNRFFDSLFPLVYNHLINPGVTDSSLEYSECIRMARRDVSPFGNIPQRVMGQMGRSLLPSRTFLQALNLGIEVINTTDYLHFSKECSRALLKMQYCPHCQGLALTKPCMGYCLNVMRGCLAHMAELNPHWHAYIRSLEELSDAMHGTYDIGHVLLNFHLLVNDAVLQAHLNGQKLLEQVNRICGRPVRTPTQSPRCSFDQSKEKHGMKTTTRNSEETLANRRKEFINSLRLYRSFYGGLADQLCANELAAADGLPCWNGEDIVKSYTQRVVGNGIKAQSGNPEVKVKGIDPVINQIIDKLKHVVQLLQGRSPKPDKWELLQLGSGGGMVEQVSGDCDDEDGCGGSGSGEVKRTLKITDWMPDDMNFSDVKQIHQTDTGSTLDTTGAGCAVAT

Approximately 60.5 kDa

Greater than 90% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.