GPNMB/Osteoactivin Protein, Human (Isoform 2, HEK293, His)

GPNMB, also known as osteoactivin, is a protein thought to have a potential role as a melanin-producing enzyme. Melanogenic enzymes are involved in the production of melanin, the pigment that determines skin, hair and eye color. GPNMB/Osteoactivin Protein, Human (Isoform 2, HEK293, His) is the recombinant human-derived GPNMB/Osteoactivin protein, expressed by HEK293 , with C-His labeled tag. The total length of GPNMB/Osteoactivin Protein, Human (Isoform 2, HEK293, His) is 453 a.a., with molecular weight of 85-90 kDa.

GPNMB, also referred to as Osteoactivin, is a protein that has been proposed to have a potential role as a melanogenic enzyme. Melanogenic enzymes are involved in the production of melanin, the pigment responsible for skin, hair, and eye color. While the exact mechanism of action of GPNMB in melanin synthesis is not fully understood, studies have suggested its involvement in this process. Further research is needed to elucidate the specific functions and regulatory mechanisms of GPNMB in melanogenesis and to determine its significance in melanin production.

Human

HEK293

C-His

Q14956-2 (A22-P474)

10457  [NCBI]

85-90 kDa

Greater than 95% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.