GUCY2C/Guanylyl cyclase C Protein, Mouse (HEK293, His)

GUCY2C, a vital guanylyl cyclase, catalyzes the synthesis of cyclic cGMP from GTP. GUCY2C/Guanylyl cyclase C Protein, Mouse (HEK293, His) is the recombinant mouse-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-6*His labeled tag.

GUCY2C, a guanylyl cyclase, plays a crucial role in catalyzing the synthesis of cyclic (cGMP) from GTP.

Immobilized Mouse GUCY2C at 5 μg/mL (100 μL/well) can bind Anti- GUCY2C Antibody. The ED₅₀ for this effect is 5.526 ng/mL, corresponding to a specific activity is 1.81×10^5 units/mg.

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  Immobilized Mouse GUCY2C at 5 μg/mL (100 μL/well) can bind Anti- GUCY2C Antibody, The ED₅₀ for this effect is 5.526 ng/mL，corresponding to a specific activity is 1.81×10⁵ units/mg.

Mouse

HEK293

C-6*His

Q3UWA6-1 (V20-M433)

14917  [NCBI]

VFWASQVRQNCRNGSYEISVLMMDNSAYKEPMQNLREAVEEGLDIVRKRLREADLNVTVNATFIYSDGLIHKSGDCRSSTCEGLDLLREITRDHKMGCALMGPSCTYSTFQMYLDTELNYPMISAGSYGLSCDYKETLTRILPPARKLMYFLVDFWKVNNASFKPFSWNSSYVYKNGSEPEDCFWYLNALEAGVSYFSEVLNFKDVLRRSEQFQEILTGHNRKSNVIVMCGTPESFYDVKGDLQVAEDTVVILVDLFSNHYFEENTTAPEYMDNVLVLTLPSEQSTSNTSVAERFSSGRSDFSLAYLEGTLLFGHMLQTFLENGENVTGPKFARAFRNLTFQGFAGPVTLDDSGDIDNIMSLLYVSLDTRKYKVLMKYDTHKNKTIPVAENPNFIWKNHKLPNDVPGLGPQILM

66-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

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  Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized a 0.22 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.