Histone H1 Protein, Human (His)

Histone H1 proteins, particularly the H1.0 variant, are crucial for condensing nucleosome chains, organizing and compacting chromatin. H1.0 is prevalent in cells undergoing terminal differentiation or with low cell division rates. Histone H1 Protein, Human (His) is the recombinant human-derived Histone H1 protein, expressed by E. coli , with N-His labeled tag. The total length of Histone H1 Protein, Human (His) is 194 a.a., with molecular weight of ~27 kDa.

Histone H1 proteins play a vital role in condensing nucleosome chains into higher-order structures, contributing to the organization and compaction of chromatin. Notably, the histone H1.0 variant is predominantly present in cells undergoing terminal stages of differentiation or exhibiting low rates of cell division.

Human

E. coli

N-His

P07305-1 (M1-K194)

3005  [NCBI]

Approximately 27 kDa

Greater than 90% as determined by reducing SDS-PAGE

Solution.

Supplied as a 0.2 μm filtered solution of 50 mM Tris, 600 mM NaCl, 1 mM DTT, pH 8.5. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.