HK3/Hexokinase-3 Protein, Human (sf9, His-GST)

The HK3 (hexokinase-3) protein promotes the phosphorylation of hexoses (i.e., D-glucose and D-fructose) to form hexose-6-phosphate (specifically, D-glucose 6-phosphate and 6-phosphate), Plays a vital role in cell metabolism. D-fructose 6-phosphate. HK3/Hexokinase-3 Protein, Human (sf9, His-GST) is the recombinant human-derived HK3/Hexokinase-3 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of HK3/Hexokinase-3 Protein, Human (sf9, His-GST) is 923 a.a., with molecular weight of ~115 kDa.

The HK3 protein, also known as Hexokinase-3, plays a crucial role in glycolysis by catalyzing the phosphorylation of hexoses, including D-glucose and D-fructose, to form hexose 6-phosphates such as D-glucose 6-phosphate and D-fructose 6-phosphate, respectively. This enzyme mediates the initial and rate-limiting step of glycolysis, facilitating the conversion of D-glucose to D-glucose 6-phosphate. Through this enzymatic activity, HK3 contributes to the entry of glucose into the glycolytic pathway, a fundamental process in cellular energy metabolism. The phosphorylation of hexoses by HK3 is essential for subsequent metabolic pathways and energy production within the cell.

Human

Sf9 insect cells

N-His;N-GST

P52790 (M1-V923)

3101  [NCBI]

Approximately 115 kDa

Greater than 85% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.