hnRNP-R Protein, Human (sf9, His-GST)

hnRNP-R Protein, a constituent of ribonucleosomes, participates in precursor mRNA processing within the nucleus. It's part of the spliceosome C complex and involved in IGF2BP1-dependent mRNP granule complexes containing untranslated mRNAs. Additionally, hnRNP-R interacts with GTPBP1. hnRNP-R Protein, Human (sf9, His-GST) is the recombinant human-derived hnRNP-R protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of hnRNP-R Protein, Human (sf9, His-GST) is 635 a.a., with molecular weight of ~114 kDa.

The hnRNP-R Protein functions as a component of ribonucleosomes, integral complexes composed of at least 20 diverse heterogeneous nuclear ribonucleoproteins (hnRNP). Operating within the nucleus, hnRNP-R and other hnRNPs play a crucial role in the processing of precursor mRNA. Notably, hnRNP-R has been identified in the spliceosome C complex and is also present in an IGF2BP1-dependent mRNP granule complex, which encompasses untranslated mRNAs. Additionally, hnRNP-R engages in interactions with GTPBP1, further contributing to its involvement in dynamic cellular processes and highlighting its multifaceted role in RNA metabolism and regulation.

Human

Sf9 insect cells

N-His;N-GST

O43390-2 (A2-K636)

10236  [NCBI]

Approximately 114 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.