1. Recombinant Proteins
  2. Cytokines and Growth Factors Biotinylated Proteins
  3. Interleukin & Receptors
  4. IL-13 Receptor
  5. IL-13Rα1
  6. IL-13R alpha 1 Protein, Human (Biotinylated, HEK293, His-Avi)

IL-13R alpha 1 Protein, Human (Biotinylated, HEK293, His-Avi)

Cat. No.: HY-P78163
Handling Instructions

The IL13RA1 protein is critical in immune signaling and binds with low affinity to IL13. It binds to IL4RA to form a functional IL13 receptor for cellular responses. IL-13R alpha 1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-His, C-Avi labeled tag.

For research use only. We do not sell to patients.

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Description

The IL13RA1 protein is critical in immune signaling and binds with low affinity to IL13. It binds to IL4RA to form a functional IL13 receptor for cellular responses. IL-13R alpha 1 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived IL-13R alpha 1 protein, expressed by HEK293 , with C-His, C-Avi labeled tag.

Background

The IL13RA1 protein plays a vital role in immune signaling, exhibiting low-affinity binding to interleukin-13 (IL13). When partnered with IL4RA, it forms a functional receptor for IL13, facilitating the cellular response to this cytokine. Additionally, IL13RA1 serves as an alternate accessory protein alongside IL4RA for interleukin-4 (IL4) signaling, although it cannot replace the function of IL2RG in enhancing interleukin-2 (IL2) binding activity. The interleukin-13 receptor is a complex assembly comprising IL4R, IL13RA1, and possibly other components, indicating the intricate architecture of this signaling system. Moreover, IL13RA1 interacts with TRAF3IP1, suggesting its involvement in diverse cellular processes. Furthermore, IL13RA1 engages in interactions with IL4, underlining its multifaceted role in mediating responses to interleukin signaling pathways.

Species

Human

Source

HEK293

Tag

C-His;C-Avi

Accession

P78552-1 (A27-T343)

Gene ID
Molecular Construction
N-term
IL-13Rα1 (A27-T343)
Accession # P78552-1
His-Avi
C-term
Synonyms
IL-13 R alpha 1; IL13R; IL13RA; CT19; IL13RA1; NR4; CD213A1; AI882074
Molecular Weight

55-75 kDa

Purity

Greater than 95% as determined by Tris-Bis PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

IL-13R alpha 1 Protein, Human (Biotinylated, HEK293, His-Avi) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
IL-13R alpha 1 Protein, Human (Biotinylated, HEK293, His-Avi)
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HY-P78163
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