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  4. IP6K1/IHPK1 Protein, Human (sf9, His-GST)

IP6K1/IHPK1 Protein, Human (sf9, His-GST)

Cat. No.: HY-P77427
Handling Instructions

IP6K1, also known as the IHPK1 protein, plays a crucial role in cell signaling by catalyzing the conversion of inositol hexaphosphate (InsP6) to inositol diphosphate pentaphosphate (InsP7/PP-InsP5). In addition, this enzyme is also involved in the conversion of 1,3,4,5,6-pentaphosphate (InsP5) to PP-InsP4. IP6K1/IHPK1 Protein, Human (sf9, His-GST) is the recombinant human-derived IP6K1/IHPK1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of IP6K1/IHPK1 Protein, Human (sf9, His-GST) is 441 a.a., with molecular weight of ~88 kDa.

For research use only. We do not sell to patients.

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Description

IP6K1, also known as the IHPK1 protein, plays a crucial role in cell signaling by catalyzing the conversion of inositol hexaphosphate (InsP6) to inositol diphosphate pentaphosphate (InsP7/PP-InsP5). In addition, this enzyme is also involved in the conversion of 1,3,4,5,6-pentaphosphate (InsP5) to PP-InsP4. IP6K1/IHPK1 Protein, Human (sf9, His-GST) is the recombinant human-derived IP6K1/IHPK1 protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of IP6K1/IHPK1 Protein, Human (sf9, His-GST) is 441 a.a., with molecular weight of ~88 kDa.

Background

The IP6K1/IHPK1 protein is an enzyme that plays a crucial role in inositol phosphate metabolism. It converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5), representing a key step in the synthesis of higher inositol polyphosphates. Additionally, IP6K1/IHPK1 catalyzes the conversion of 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. These enzymatic activities contribute to the intricate regulation of inositol phosphate signaling, which is involved in diverse cellular processes such as cell growth, vesicular trafficking, and ion channel regulation. The conversion of InsP6 to InsP7/PP-InsP5 and InsP5 to PP-InsP4 highlights the significance of IP6K1/IHPK1 in modulating inositol phosphate levels, thereby influencing various cellular functions (

Species

Human

Source

Sf9 insect cells

Tag

N-His;N-GST

Accession

Q92551 (M1-Q441)

Gene ID
Molecular Construction
N-term
His-GST
IP6K1 (M1-Q441)
Accession # Q92551
C-term
Synonyms
Inositol hexakisphosphate kinase 1; InsP6 kinase 1; IHPK1; KIAA0263
Molecular Weight

Approximately 88 kDa

Purity

Greater than 85% as determined by reducing SDS-PAGE

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

IP6K1/IHPK1 Protein, Human (sf9, His-GST) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
IP6K1/IHPK1 Protein, Human (sf9, His-GST)
Cat. No.:
HY-P77427
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