MAGP-2/MFAP5 Protein, Mouse (HEK293, Fc)

The MAGP-2/MFAP5 protein potentially contributes to hematopoiesis and regulates growth factors in the cardiovascular system. It supports elastin's structural framework and interacts with TGFB2, BMP2, FBN1, and FBN2, crucial for tissue architecture. Studying MAGP-2/MFAP5's mechanisms in hematopoiesis and cardiovascular interactions could unveil its broader physiological roles. MAGP-2/MFAP5 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived MAGP-2/MFAP5 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of MAGP-2/MFAP5 Protein, Mouse (HEK293, Fc) is 136 a.a., with molecular weight of 36 kDa & 52-57 kDa, respectively.

The MAGP-2/MFAP5 protein may contribute to hematopoiesis, indicating a potential role in the formation and development of blood cells. Within the cardiovascular system, it could regulate growth factors and participate in cell signaling to maintain the integrity of large vessels. As a component of the elastin-associated microfibrils, MAGP-2/MFAP5 is involved in the structural framework that supports elastin. It interacts with TGFB2, suggesting a potential role in the regulation of transforming growth factor-beta signaling. Additionally, MAGP-2/MFAP5 interacts with BMP2, FBN1 (via the N-terminal domain), and FBN2, indicating its involvement in various protein-protein interactions crucial for maintaining tissue architecture and function. Further exploration of MAGP-2/MFAP5's specific mechanisms in hematopoiesis and its interactions within the cardiovascular system could provide valuable insights into its broader roles in physiological processes.

Mouse

HEK293

C-hFc

Q9QZJ6 (Q29-L164)

50530  [NCBI]

36 kDa&52-57 kDa

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized powder

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.