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  5. PDGF-R-alpha PDGFR
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  7. PDGF R alpha Protein, Cynomolgus (501a.a, HEK293, His)

PDGF R alpha Protein, Cynomolgus (501a.a, HEK293, His)

Cat. No.: HY-P700809
Handling Instructions

PDGF R alpha Protein, a tyrosine-protein kinase receptor, crucially influences embryonic development, regulating cell proliferation, survival, and chemotaxis. Its effects on cell behavior vary contextually, either promoting or inhibiting proliferation and migration. Additionally, it plays a significant role in differentiating bone marrow-derived mesenchymal stem cells and is essential for normal skeletal development. PDGF R alpha Protein, Cynomolgus (501a.a, HEK293, His) is the recombinant cynomolgus-derived PDGF R alpha protein, expressed by HEK293 , with C-His labeled tag. The total length of PDGF R alpha Protein, Cynomolgus (501a.a, HEK293, His) is 501 a.a., with molecular weight of 70-85 kDa.

For research use only. We do not sell to patients.

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Description

PDGF R alpha Protein, a tyrosine-protein kinase receptor, crucially influences embryonic development, regulating cell proliferation, survival, and chemotaxis. Its effects on cell behavior vary contextually, either promoting or inhibiting proliferation and migration. Additionally, it plays a significant role in differentiating bone marrow-derived mesenchymal stem cells and is essential for normal skeletal development. PDGF R alpha Protein, Cynomolgus (501a.a, HEK293, His) is the recombinant cynomolgus-derived PDGF R alpha protein, expressed by HEK293 , with C-His labeled tag. The total length of PDGF R alpha Protein, Cynomolgus (501a.a, HEK293, His) is 501 a.a., with molecular weight of 70-85 kDa.
Background

PDGF R alpha Protein is a tyrosine-protein kinase that serves as a cell-surface receptor for PDGFA, PDGFB, and PDGFC. It plays a crucial role in embryonic development, regulating cell proliferation, survival, and chemotaxis. Its function can either promote or inhibit cell proliferation and migration, depending on the context. Additionally, it plays a significant role in the differentiation of mesenchymal stem cells derived from the bone marrow. Furthermore, PDGF R alpha Protein is essential for normal skeletal development.
Species

Cynomolgus
Source

HEK293
Tag

C-His
Accession

Q0PW86 (Q24-E524)
Gene ID

102138392
Molecular Construction
N-term
PDGF R alpha (Q24-E524)
Accession # Q0PW86
His
C-term
Synonyms
PDGFRA; CD140A; PDGFR2; RHEPDGFRA; MGC74795; PDGFR-2
Molecular Weight

70-85 kDa
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

PDGF R alpha Protein, Cynomolgus (501a.a, HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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