PSMP Protein, Mouse (HEK293, Fc)

PSMP protein, acting as a CCR2 ligand, induces a robust chemotactic response and intracellular calcium mobilization in monocytes and lymphocytes, while having no impact on neutrophils. PSMP Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived PSMP protein, expressed by HEK293 , with C-hFc labeled tag. The total length of PSMP Protein, Mouse (HEK293, Fc) is 103 a.a., with molecular weight of 48-51 kDa.

PSMP protein functions as a ligand for C-C chemokine receptor CCR2, initiating a potent chemotactic response and intracellular calcium mobilization through CCR2 binding and activation. It demonstrates chemotactic activity for monocytes and lymphocytes but does not affect neutrophils.

Mouse

HEK293

C-hFc

B1AWI6 (K37-S139)

100039672  [NCBI]

45-53 kDa

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized powder

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.