PTP4A1 Protein, Human (His)

The PTP4A1 protein is an active tyrosine phosphatase that not only stimulates the G1 to S phase progression of mitosis but also plays a crucial role in the development and maintenance of differentiated epithelial tissues. Its multifunctional contribution extends to cell differentiation, profoundly affecting cell behavior by enhancing proliferation, motility, and invasive activity. PTP4A1 Protein, Human (His) is the recombinant human-derived PTP4A1 protein, expressed by E. coli , with N-His labeled tag. The total length of PTP4A1 Protein, Human (His) is 170 a.a., with molecular weight of 20.56 kDa.

PTP4A1 protein, a dynamic protein tyrosine phosphatase, emerges as a key regulator that stimulates the progression from G1 into S phase during mitosis. Beyond its mitotic role, PTP4A1 is implicated in the development and maintenance of differentiating epithelial tissues, underscoring its versatile contributions to cellular differentiation. Notably, PTP4A1 exhibits a profound impact on cellular behavior, enhancing cell proliferation, motility, and invasive activity. In the context of cancer, PTP4A1 takes on a pivotal role, promoting metastasis. Its multifaceted functions highlight the crucial involvement of PTP4A1 in orchestrating diverse cellular processes, with implications for both normal tissue development and pathological conditions associated with cancer progression and metastasis.

Human

E. coli

N-His

Q93096 (M1-C170)

7803  [NCBI]

20.56 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.