RGM-C Protein, Mouse (HEK293, His)

RGM-C Protein, a BMP coreceptor, crucially regulates hepcidin (HAMP) expression, influencing iron homeostasis through enhanced BMP signaling. It forms a molecular network by interacting with BMP2, BMP4, BMP6, BMPR1B, and TMPRSS6, collectively mediating BMP-related signaling pathways and modulating iron regulatory processes. RGM-C Protein, Mouse (HEK293, His) is the recombinant mouse-derived RGM-C protein, expressed by HEK293, with C-His labeled tag. The total length of RGM-C Protein, Mouse (HEK293, His) is 361 a.a., with molecular weight of 55-60 kDa & 36-40 kDa & 20-25 kDa, respectively.

RGM-C serves as a bone morphogenetic protein (BMP) coreceptor, playing a pivotal role in the regulation of hepcidin (HAMP) expression and influencing iron homeostasis by enhancing BMP signaling. It interacts with BMP2, BMP4, BMP6, BMPR1B, and TMPRSS6, establishing a network of molecular associations that collectively contribute to its role in mediating BMP-related signaling pathways and modulating iron regulatory processes.

Mouse

HEK293

C-His

Q7TQ32-1 (G33-A393)

69585  [NCBI]

55-60 kDa&36-40 kDa&20-25 kDa

Greater than 95% as determined by Tris-Bis PAGE.

<1 EU/μg, determined by LAL method.