RPS7 Protein, Human (His)

RPS7 is an important component of the small ribosomal subunit and is essential for cellular protein synthesis. Within the small subunit (SSU) processome, RPS7 contributes to rRNA maturation and is actively involved in SSU processome assembly in the nucleolus. RPS7 Protein, Human (His) is the recombinant human-derived RPS7 protein, expressed by E. coli , with C-6*His labeled tag. The total length of RPS7 Protein, Human (His) is 194 a.a., with molecular weight of ~23.0 kDa.

RPS7, an integral component of the small ribosomal subunit, plays a vital role in the synthesis of cellular proteins. As part of the small subunit (SSU) processome, the initial precursor of the small eukaryotic ribosomal subunit, RPS7 contributes to rRNA maturation and is actively engaged in the assembly of the SSU processome within the nucleolus. In this intricate process, numerous ribosome biogenesis factors, an RNA chaperone, and ribosomal proteins, including RPS7, collaborate to facilitate RNA folding, modifications, rearrangements, and cleavage. Additionally, RPS7 participates in the targeted degradation of pre-ribosomal RNA by the RNA exosome. A key participant in the SSU processome, comprised of more than 70 proteins and the RNA chaperone small nucleolar RNA (snoRNA) U3, RPS7 interacts with various proteins, such as IPO9, NEK6, DESI2, IPO5, IPO7, and KPNB1, highlighting its multifaceted role in ribosomal subunit assembly and nuclear import processes.

Human

E. coli

C-6*His

P62081 (M1-L194)

6201  [NCBI]

MFSSSAKIVKPNGEKPDEFESGISQALLELEMNSDLKAQLRELNITAAKEIEVGGGRKAIIIFVPVPQLKSFQKIQVRLVRELEKKFSGKHVVFIAQRRILPKPTRKSRTKNKQKRPRSRTLTAVHDAILEDLVFPSEIVGKRIRVKLDGSRLIKVHLDKAQQNNVEHKVETFSGVYKKLTGKDVNFEFPEFQL

Approximately 23.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.