2. Recombinant Proteins
  3. Immune Checkpoint Proteins Receptor Proteins Biotinylated Proteins
  4. Inhibitory Checkpoint Molecules Siglec
  5. Siglec-9
  6. Siglec-9 Protein, Human (HEK293, His-Avi)

Siglec-9 Protein, Human (HEK293, His-Avi)

Cat. No.: HY-P78040
Handling Instructions

Siglec-9 Protein, a putative adhesion molecule, mediates sialic-acid dependent cellular binding with a preference for alpha-2,3- or alpha-2,6-linked sialic acid. Its sialic acid recognition site may undergo masking through cis interactions with sialic acids on the same cell surface. Siglec-9 Protein, Human (HEK293, His-Avi) is the recombinant human-derived Siglec-9 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

For research use only. We do not sell to patients.

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Description

Siglec-9 Protein, a putative adhesion molecule, mediates sialic-acid dependent cellular binding with a preference for alpha-2,3- or alpha-2,6-linked sialic acid. Its sialic acid recognition site may undergo masking through cis interactions with sialic acids on the same cell surface. Siglec-9 Protein, Human (HEK293, His-Avi) is the recombinant human-derived Siglec-9 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.
Background

Siglec-9 protein, identified as a putative adhesion molecule, serves as a mediator in sialic-acid dependent cellular binding. It exhibits a preference for binding to alpha-2,3- or alpha-2,6-linked sialic acid. Notably, the sialic acid recognition site of Siglec-9 may undergo masking due to cis interactions with sialic acids on the same cell surface.
Species

Human
Source

HEK293
Tag

C-Avi;C-His
Accession

Q9Y336-1 (Q18-G348)
Gene ID
Molecular Construction
N-term
Siglec-9 (Q18-G348)
Accession # Q9Y336-1
His-Avi
C-term
Synonyms
CD329; CDw329; FOAP-9; OBBP-Like; Siglec-9; SIGLEC9
Molecular Weight

70-80 kDa
Purity

Greater than 95% as determined by Tris-Bis PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

Siglec-9 Protein, Human (HEK293, His-Avi) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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