Syntaxin-3 Protein, Human (His)

Syntaxin-3 protein plays a potentially critical role in docking synaptic vesicles at the presynaptic zone, suggesting a role in regulating neurotransmitter release. Furthermore, it is also implicated as an apical receptor in apical vesicle membrane fusion, suggesting a broader involvement in intracellular trafficking. Syntaxin-3 Protein, Human (His) is the recombinant human-derived Syntaxin-3 protein, expressed by E. coli , with N-His labeled tag. The total length of Syntaxin-3 Protein, Human (His) is 289 a.a., with molecular weight of ~37 kDa.

Syntaxin-3 Protein emerges as a potential key player in the docking of synaptic vesicles at presynaptic active zones, indicating its probable role in regulating neurotransmitter release. Additionally, it is implicated as an apical receptor involved in the membrane fusion of apical vesicles, suggesting a broader involvement in intracellular vesicle trafficking and fusion processes. Notably, Syntaxin-3 is deemed essential for the survival of retinal photoreceptors, underlining its critical role in maintaining the structural and functional integrity of these specialized cells. The diverse functions attributed to Syntaxin-3 underscore its significance in neuronal signaling and cellular processes, warranting further exploration to unravel the specific molecular mechanisms underlying its involvement in synaptic function and retinal homeostasis.

Human

E. coli

N-His

Q13277 (M1-N289)

6809  [NCBI]

Approximately 37 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.