THSD7A Protein, Human (HEK293, His)

THSD7A Protein orchestrates actin cytoskeleton rearrangement, actively influencing cellular dynamics. Its soluble form facilitates endothelial cell migration and filopodia formation in sprouting angiogenesis, relying on Focal Adhesion Kinase (FAK) activation. This emphasizes THSD7A's role in modulating key cellular processes associated with angiogenesis, highlighting its potential as a regulator of vascular development. THSD7A Protein, Human (HEK293, His) is the recombinant human-derived THSD7A protein, expressed by HEK293 , with C-His labeled tag. The total length of THSD7A Protein, Human (HEK293, His) is 1560 a.a., with molecular weight of 180-240 kDa.

THSD7A orchestrates actin cytoskeleton rearrangement, exerting its influence on cellular dynamics. Notably, its soluble form emerges as a facilitator of endothelial cell migration and filopodia formation in the context of sprouting angiogenesis, operating through a mechanism reliant on FAK (Focal Adhesion Kinase) activation. This underscores its active involvement in modulating key cellular processes associated with angiogenesis and highlights its potential as a regulator of vascular development.

Human

HEK293

C-His

Q9UPZ6 (A48-W1607)

221981  [NCBI]

180-240 kDa

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized powder

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4)

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.