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  6. Retrorsine N-oxide

Retrorsine N-oxide, an N-oxide of pyrrolizidine alkaloid, is a carcinogen. Retrorsine N-oxide-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides.

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Retrorsine N-oxide Chemical Structure

Retrorsine N-oxide Chemical Structure

CAS No. : 15503-86-3

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Retrorsine N-oxide Related Antibodies

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Description

Retrorsine N-oxide, an N-oxide of pyrrolizidine alkaloid, is a carcinogen. Retrorsine N-oxide-derived DNA adducts are common toxicological biomarkers of pyrrolizidine alkaloid N-oxides[1][2].

In Vivo

Retrorsine N-oxide produces DNA adducts, the common biological biomarker of PA-induced liver tumor formation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

367.39

Formula

C18H25NO7
CAS No.
SMILES

O=C(/C(C[C@H]([C@@](O)(C(OCC1=CC2)=O)CO)C)=C\C)O[C@@]3([H])[C@]1([H])[N+]2([O-])CC3
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Retrorsine N-oxide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Retrorsine N-oxide15503-86-3OtherspyrrolizidinecarcinogenbiomarkerDNAcancerlivertumorInhibitorinhibitorinhibit

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