2. Metabolic Enzyme/Protease
  3. Aldose Reductase
  4. Rhetsinine

Rhetsinine is an aldose reductase inhibitor isolated from Evodia rutaecarpa, exhibiting an IC50 value of 24.1 μM. At a concentration of 100 μM, rhetsinine significantly inhibits sorbitol accumulation by 79.3%. This compound shows potential for research in diabetic complications, including diabetic neuropathy and retinopathy.

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Rhetsinine Chemical Structure

Rhetsinine Chemical Structure

CAS No. : 526-43-2

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Rhetsinine Related Antibodies

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Description

Rhetsinine is an aldose reductase inhibitor isolated from Evodia rutaecarpa, exhibiting an IC50 value of 24.1 μM. At a concentration of 100 μM, rhetsinine significantly inhibits sorbitol accumulation by 79.3%. This compound shows potential for research in diabetic complications, including diabetic neuropathy and retinopathy[1].

Molecular Weight

319.36

Formula

C19H17N3O2
CAS No.
SMILES

O=C(N1C(C2=C(CC1)C3=C(C=CC=C3)N2)=O)C4=C(NC)C=CC=C4
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Rhetsinine Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rhetsinine526-43-2Aldose ReductaseInhibitorinhibitorinhibit

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